Abstract
Young-onset Parkinson’s disease (YOPD) is arbitrarily defined as Parkinson’s disease which produces initial symptoms between ages 21 and 39. YOPD appears to be the same nosologic entity as older-onset Parkinson’s disease (PD). It accounts for approximately 5% of PD referrals in Western countries and about 10% in Japan. Compared with older-onset PD, the available evidence suggests that YOPD patients have (1) slower disease progression, (2) an increased frequency of dystonia at onset and during treatment, (3) a lower occurrence of dementia, and (4) an increased risk of dyskinesias in response to levodopa treatment. YOPD appears to form a heterogeneous patient group with a higher proportion of cases due to genetic causes.
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References
1.Golbe LI. Young-onset Parkinson’s disease: a clinical review. Neurology. 1991;41:168–73.
2.Quinn N, Critchley P, Marsden CD. Young onset Parkinson’s disease. Mov Disord. 1987; 2:73–91.
3.Wickremaratchi MM, Ben-Shlomo Y, Morris HR. The effect of onset age on the clinical features of Parkinson’s disease. Eur J Neurol. 2009;16:450–6.
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Gait and turns are normal but left arm swing is reduced. There is facial masking. Left-sided rapid hand movements and finger tapping are markedly bradykinetic.
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Bhidayasiri, R., Tarsy, D. (2012). Young-Onset Parkinson’s Disease. In: Movement Disorders: A Video Atlas. Current Clinical Neurology. Humana, Totowa, NJ. https://doi.org/10.1007/978-1-60327-426-5_3
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DOI: https://doi.org/10.1007/978-1-60327-426-5_3
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Publisher Name: Humana, Totowa, NJ
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