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Handbook of Cardiac Anatomy, Physiology, and Devices pp 87–108Cite as

Comparative Cardiac Anatomy

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Abstract

The need for appropriate animal models to conduct translational research is vital for advancements in the diagnosis and treatment of heart disease. The choice of animal model to be employed must be critically evaluated. In this chapter, we present the comparative cardiac anatomy of several of the commonly employed animal models (dog, pig, and sheep). A general comparison focuses on several specific anatomic features: the atria, the ventricles, the valves, the coronary system, lymphatics, and the conduction system. Finally, we present novel qualitative and quantitative data that we have obtained from perfusion fixed specimens of the most commonly used animal models.

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Authors and Affiliations

  1. Department of Surgery, University of Minnesota and Medtronic, Inc, 8299 Central Ave. NE, Minneapolis, MN 55455, USA

    Alexander J. Hill

  2. Department of Surgery, University of Minnesota, B 172 Mayo, MMC 195, 420 Delaware St. SE, Minneapolis, MN 55455, USA

    Paul A. Iaizzo

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  1. Alexander J. Hill
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  2. Paul A. Iaizzo
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Correspondence to Alexander J. Hill .

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Editors and Affiliations

  1. Dept. Surgery, University of Minnesota, Delaware St. SE., 420, Minneapolis, 55455, U.S.A.

    Paul A. Iaizzo

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Hill, A.J., Iaizzo, P.A. (2009). Comparative Cardiac Anatomy. In: Iaizzo, P. (eds) Handbook of Cardiac Anatomy, Physiology, and Devices. Humana Press. https://doi.org/10.1007/978-1-60327-372-5_6

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  • DOI: https://doi.org/10.1007/978-1-60327-372-5_6

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