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Immune Tolerance

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National Institute of Allergy and Infectious Diseases, NIH

Part of the book series: Infectious Disease ((ID))

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Immune tolerance holds the key to controlling unwanted immunologic attacks on self and transplanted tissues. Alloreactive responses to transplanted tissues and organs have long been recognized as among the most powerful known in immunology, being at least 100-fold greater than those elicited by conventional antigens; such responses require potent, nonspecific immunosuppression to maintain organ allografts in clinical practice. In contrast, autoimmune diseases involve the loss of tolerance to self-antigens (1).

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    Vassil St. Georgiev PhD

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Georgiev, V.S. (2009). Immune Tolerance. In: Georgiev, V.S. (eds) National Institute of Allergy and Infectious Diseases, NIH. Infectious Disease. Humana Press. https://doi.org/10.1007/978-1-60327-297-1_40

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