Abstract
A normal kidney regulatory function is essential in order to maintain optimal body fluid dynamics and preserve electrolyte homeostasis. Similarly, a good kidney function is dependent on adequacy of its perfusion. The initial phase of this review will highlight the progress made so far in a consensus definition of acute kidney injury (AKI). Emphasis on the prospect of a future application of tissue biomarkers as a more accurate diagnostic tool will follow. Second, the pathogenesis and clinical outcome of pre-renal azotemia and intrinsic AKI will be differentiated. The mechanisms of renal injury in the course of fluid and electrolyte disorders are then discussed. Finally, clinical management of AKI and the challenges of fluid and electrolyte status in surgical kidney transplantation are delineated.
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Bamgbola, O.F. (2010). Special Consideration on Fluid and Electrolytes in Acute Kidney Injury and Kidney Transplantation. In: Feld, L., Kaskel, F. (eds) Fluid and Electrolytes in Pediatrics. Nutrition and Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-60327-225-4_13
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