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Aortic Aneurysms pp 27–34Cite as

Inflammatory Pathogenesis and Pathophysiology of Abdominal Aortic Aneurysms

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Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

The aorta is a high-pressure conduit that also conserves the energy output of the heart (elastic recoil). The main structural proteins of the aorta — collagen and elastin — serve these functions. The aortic architecture is not uniform and varies from the thoracic aorta to the infrarenal aorta. With these basic understandings of the aortic structure and function in mind, it is clear that inflammation, genetics, and mechanical forces play important roles in the pathogenesis of abdominal aortic aneurysms. Additional research is needed to further understand the relationship between these factors.

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Authors and Affiliations

  1. Department of Surgery, Division of Vascular Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL

    William H. Pearce & Vera P. Shively

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  1. William H. Pearce
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  2. Vera P. Shively
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Editors and Affiliations

  1. Department of Surgery Sec. Vascular Surgery, University of Michigan Health System, 1500 E. Medical Center Dr., TC2210N, Ann Arbor, MI, 48109-0329, USA

    Gilbert R. Upchurch Jr.  & Enrique Criado  & 

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Pearce, W.H., Shively, V.P. (2009). Inflammatory Pathogenesis and Pathophysiology of Abdominal Aortic Aneurysms. In: Upchurch, G.R., Criado, E. (eds) Aortic Aneurysms. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-60327-204-9_2

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  • DOI: https://doi.org/10.1007/978-1-60327-204-9_2

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-60327-203-2

  • Online ISBN: 978-1-60327-204-9

  • eBook Packages: MedicineMedicine (R0)

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