Abstract
Hydrogels are materials with the ability to swell in water through the retention of significant fractions of water within their structures. Owing to their relatively high degree of biocompatibility, hydrogels have been utilized in a host of biomedical applications. In an attempt to determine the optimum conditions for hydrogel synthesis by the free-radical polymerization of sorbitan methacrylate (SMA), the hydrogel used in this study was well polymerized under the following conditions: 50% (w/v) SMA as monomer, 1% (w/w) α, α′-azo-bis(isobutyro-nitrile) as thermal initiator, and 1% (w/w) ethylene glycol dimethacrylate as cross-liking agent. Under these conditions, the moisture content of the polymerized SMA hydrogel was higher than in the other conditions. Moreover, the moisture content of the poly(SMA) hydrogel was also found to be higher than that of the poly(methyl methacrylate [MMA]) hydrogel. When the Fourier transform-infrared spectrum of poly(SMA) hydrogel was compared with that of poly(MMA) hydrogel, we noted a band at 1735-1730/cm, which did not appear in the Fourier transform-infrared spectrum of poly(MMA). The surface of the poly(SMA) hydrogel was visualized through scanning electron microscopy, and was uniform and clear in appearance.
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References
Hanks, C. T., John, C. W., and Sun, Z. (1996), Dent. Mater. 12, 186–193.
Park, D. W. (2003), PhD Dissertation, Yonsei University, Seoul, Korea.
Jeong, G. T., Byun, K. Y., Lee, W. T., et al. (2006), Biochem. Eng. J. 29, 69–74.
Jeong, G. T., Lee, H. J., Kim, H. S., and Park, D. H. (2006), Appl. Biochem. Biotechnol. 129–132, 265–277.
Park, D. W. and Kim, H. S. (2004), J. Korean Oil Chem. Soc. 21, 37–44.
Berger, J., Reist, M., Mayer, J. M., Felt, O., Peppas, N. A., and Gurny, R. (2004), Eur. J. Pharm. Biopharm. 57, 19–34.
Jeong, G. T. and Park, D. H. (2006), Enzyme Microbiol. Technol. (in press).
Taguchi, T., Kishida, A., Sakamoto, N., and Akashi, M. (1998), J. Biomed. Mater. Res. 41, 386–391.
Coviello, T., Grassi, M., Rambone, G., et al. (1999), J. Controlled Release 60, 367–378.
Kim, S. K., Shin, J. S., Moon, Y. U., and Lee, K. Y. (1996), J. Korean Ind. Eng. Chem. 7, 136–144.
Cunningham, M. F. (2002), Prog. Polym. Sci. 27, 1039–1067.
Jalbert, I. and Stapleton, F. (2005), Contact Lens Anterior Eye 28, 3–12.
Liu, Z. and Pflugfelder, S. C. (2000), Ophthalmology 107, 105–111.
Magnani, A., Rappuoli, R., Lamponi, S., and Barbucci, R. (2000), Adv. Technol. 11, 488–495.
Chen, X., Martin, B. D., Neubauer, T. K., Linharbt, R. J., Dordick, J. S., and Rethwisch, D. G. (1995), Carbohydr. Polym. 28, 15–21.
Draye, J. P., Delaey, B., de Voorde, A. V., Bulcke, A. V. D., Reu, B. D., and Schacht, E. (1998), Biomaterials 19, 1677–1687.
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Jeong, GT. et al. (2007). Synthesis of Poly(Sorbitan Methacrylate) Hydrogel by Free-Radical Polymerization. In: Mielenz, J.R., Klasson, K.T., Adney, W.S., McMillan, J.D. (eds) Applied Biochemistry and Biotecnology. ABAB Symposium. Humana Press. https://doi.org/10.1007/978-1-60327-181-3_76
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DOI: https://doi.org/10.1007/978-1-60327-181-3_76
Publisher Name: Humana Press
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