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Holt-Oram Syndrome

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Atlas of Genetic Diagnosis and Counseling

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Abstract

In 1960, Holt and Oram described a family in which nine members in four generations were affected by skeletal abnormalities of the upper limbs, cardiac malformations, and arrhythmias. The prevalence is about 1 in 100,000 live births. About 40 to 85% of cases are due to fresh mutation.

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© 2006 Humana Press Inc.

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(2006). Holt-Oram Syndrome. In: Atlas of Genetic Diagnosis and Counseling. Humana Press. https://doi.org/10.1007/978-1-60327-161-5_95

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  • DOI: https://doi.org/10.1007/978-1-60327-161-5_95

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-681-8

  • Online ISBN: 978-1-60327-161-5

  • eBook Packages: MedicineMedicine (R0)

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