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Liver Transplantation pp 65–89Cite as

The Dilemma of Adult-to-Adult Living Donor Liver Transplantation

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Abstract

Adult-to-adult living donor liver transplantation (aLDLT) has rapidly evolved in less than a decade. In countries with a robust deceased donor-organ allocation, only about 3–4% of all liver transplantations are aLDLT. Several types of living donor grafts may be utilized for aLDLT. The donor morbidity and mortality represent short- and long-term impediments to further application of aLDLT, and our understanding of the donor risks associated with this procedure continues to evolve. The outcomes of aLDLT are favorable, and pursuing aLDLT may offer a survival advantage compared to candidates who do not have a potential living donor. The application of aLDLT in different regions of the world is discussed. In addition, the special issues related to aLDLT in patients with hepatocellular carcinoma and those infected with hepatitis C are reviewed.

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  1. Department of Surgery, Center for Liver Disease and Transplantation, The New York Presbyterian Hospital, New York, NY

    John F. Renz MD, PHD

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    Renz, J.F., Brown, R.S. (2009). The Dilemma of Adult-to-Adult Living Donor Liver Transplantation. In: Trotter, J., Everson, G. (eds) Liver Transplantation. Clinical Gastroenterology. Humana Press. https://doi.org/10.1007/978-1-60327-028-1_4

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