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Overlap Syndromes of Autoimmune Hepatitis With Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis

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Liver Immunology

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Abstract

The term “overlap syndrome” has been introduced to the field of hepatology to describe variant forms of autoimmune hepatitis (AIH) which present with the characteristics of AIH on the one hand and primary biliary cirrhosis (PBC) or primary sclerosing cholangitis (PSC) on the other hand. There is still controversy over whether these “overlap syndromes” form distinct entities or are only variants of the major autoimmune hepatopathies. Standardization of diagnostic criteria for overlap syndromes has not been achieved so far, and misuse of the term “overlap syndrome” is common in clinical practice (1).

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Author information

Authors and Affiliations

  1. Department of Gastroenterology and Hepatology, ANC, University of Amsterdam, Amsterdam, The Netherlands

    Ulrich Beuers MD

  2. Department of Medicine II, Klinikum Grosshadern, University of Munich, Munich, Germany

    Christian Rust MD

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  1. Ulrich Beuers MD
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  2. Christian Rust MD
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Editor information

Editors and Affiliations

  1. Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, Davis, CA

    M. Eric Gershwin MD, FACP

  2. Departments of Medicine and Surgery Baylor Liver Health, Baylor College of Medicine, Houston, TX

    John M. Vierling MD, FACP

  3. Department of Gastroenterology, Hepatology, and Endocrinology, Medical School of Hannover, Hannover, Germany

    Michael P. Manns MD

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© 2007 Humana Press Inc., Totowa, NJ

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Beuers, U., Rust, C. (2007). Overlap Syndromes of Autoimmune Hepatitis With Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis. In: Gershwin, M.E., Vierling, J.M., Manns, M.P. (eds) Liver Immunology. Humana Press. https://doi.org/10.1007/978-1-59745-518-3_23

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  • DOI: https://doi.org/10.1007/978-1-59745-518-3_23

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-818-8

  • Online ISBN: 978-1-59745-518-3

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