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Thyroid Autoantigens

  • Philip F. Watson
  • Nagat Saeed
Part of the Contemporary Endocrinology book series (COE)

Summary

Identification and characterization of key antigenic targets is an important step in understanding the development and pathogenic mechanisms of autoimmune disease. Fifty years after the initial description of thyroid autoimmunity and identification of the major autoantigens, the disease remains the best understood form of human organ-specific autoimmunity. The structure and function of the major thyroid antigens, together with recent advances in our understanding of the corresponding autoimmune responses to these targets, will be discussed in this chapter

Keywords

Thyroglobulin thyroid peroxidase thyrotropin receptor thyroid-stimulating antibodies epitopes 

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Copyright information

© Humana Press Inc. 2007

Authors and Affiliations

  • Philip F. Watson
  • Nagat Saeed

There are no affiliations available

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