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Deep Brain Stimulation for Obsessive-Compulsive Disorder and Major Depressive Disorder

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Psychiatric Neurotherapeutics

Part of the book series: Current Clinical Psychiatry ((CCPSY))

Abstract

A subset of patients with obsessive-compulsive disorder (OCD) and major depressive disorder (MDD) are not responsive to medication or psychological/behavioral therapies. After other avenues of treatment have been attempted, neurosurgery, including deep brain stimulation (DBS), has been used as a treatment for the most severe and refractory patients. In this chapter, we will review the therapeutic use of DBS for OCD and MDD, discussing its history, current practice, results from clinical and translational research, clinical indications, and safety issues relevant to this technique.

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Author information

Authors and Affiliations

  1. Butler Hospital, Providence, RI, USA

    Nicole C. R. McLaughlin Ph.D., Catherine Stewart & Benjamin D. Greenberg

  2. Alpert Medical School of Brown University, Providence, RI, USA

    Nicole C. R. McLaughlin Ph.D.

  3. Boston Medical Center, Providence, RI, USA

    Catherine Stewart

Authors
  1. Nicole C. R. McLaughlin Ph.D.
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  2. Catherine Stewart
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  3. Benjamin D. Greenberg
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Corresponding author

Correspondence to Nicole C. R. McLaughlin Ph.D. .

Editor information

Editors and Affiliations

  1. Medical School, Dept of Psychiatry, Massachusetts Gen Hosp, Harvard, Boston, Massachusetts, USA

    Joan A. Camprodon

  2. McLean Hospital, Belmont, Massachusetts, USA

    Scott L. Rauch

  3. Butler Hospital, Providence, Rhode Island, USA

    Benjamin D. Greenberg

  4. Harvard Medical School, Charleston, Massachusetts, USA

    Darin D. Dougherty

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McLaughlin, N.C.R., Stewart, C., Greenberg, B.D. (2016). Deep Brain Stimulation for Obsessive-Compulsive Disorder and Major Depressive Disorder. In: Camprodon, J., Rauch, S., Greenberg, B., Dougherty, D. (eds) Psychiatric Neurotherapeutics. Current Clinical Psychiatry. Humana Press, New York, NY. https://doi.org/10.1007/978-1-59745-495-7_7

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  • DOI: https://doi.org/10.1007/978-1-59745-495-7_7

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