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Airway Management and Mechanical Ventilation in Pregnancy

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Pulmonary Problems in Pregnancy

Abstract

Anesthesia-related maternal mortality rates have improved in the United States, but it still remains a prominent cause of maternal mortality. Anesthesia is the seventh leading cause of maternal mortality in the United States with the top six causes being embolism, hypertensive disorders, hemorrhage, infection, cardiomyopathy, and cerebrovascular accident (1). General anesthesia is more likely to be associated with maternal mortality than regional anesthesia in the obstetric patient for the following reasons: (1) airway management tends to be more difficult in pregnant patients due to altered anatomy and physiology; (2) general anesthesia is chosen in emergency surgeries when there is no time for adequate preoperative evaluation and aspiration prophylaxis; (3) conversion of regional anesthetic to general anesthesia for inadequate block, hemorrhage, etc., with the patient not in the optimal position for intubation; and (4) increased usage of regional anesthesia in obstetrics with minimal exposure of trainees to general anesthesia for cesarean sections, resulting in decreased airway management skills for training and maintenance in the obstetric patient.

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References

  1. Hawkins JL. Anesthesia-related maternal mortality. Clin Obstet Gynecol 2003;46(3):679–687.

    Article  PubMed  Google Scholar 

  2. Lewin SB, Cheek TG, Deutschman CS. Airway management in the obstetric patient. Crit Care Clin 2000;16(3):505–513.

    Article  PubMed  CAS  Google Scholar 

  3. Hawthorne L, Wilson R, Lyons G, Dresner M. Failed intubation revisited: 17-yr experience in a teaching maternity unit. Br J Anaesth 1996;76(5):680–684.

    PubMed  CAS  Google Scholar 

  4. Jouppila R, Jouppila P, Hollmen A. Laryngeal oedema as an obstetric anaesthesia complication: case reports. Acta Anaesthesiol Scand 1980;24(2):97–98.

    Article  PubMed  CAS  Google Scholar 

  5. Kuczkowski KM, Reisner LS, Benumof JL. Airway problems and new solutions for the obstetric patient. J Clin Anesth 2003;15(7):552–563.

    Article  PubMed  Google Scholar 

  6. Norwitz ER, Robinson JN, Malone FD. Pregnancy-induced physiologic alterations. In: Dildy GA, Belfort MA, Saade GR, Phelan JP, Hankins GD, Clark SL, editors. Critical Care Obstetrics. 4th ed. Malden, MA: Blackwell Science; 2004 p. 19–42.

    Chapter  Google Scholar 

  7. Seager SJ, Macdonald R. Laryngeal oedema and pre-eclampsia. Anaesthesia 1980;35(4):360–362.

    Article  PubMed  CAS  Google Scholar 

  8. Brimacombe J. Acute pharyngolaryngeal oedema and pre-eclamptic toxaemia. Anaesth Intensive Care 1992;20(1):97–98.

    PubMed  CAS  Google Scholar 

  9. Brock-Utne JG, Downing JW, Seedat F. Laryngeal oedema associated with pre-eclamptic toxaemia. Anaesthesia 1977;32(6):556–558.

    Article  PubMed  CAS  Google Scholar 

  10. O'Sullivan G, Scrutton M. NPO during labor. Is there any scientific validation? Anesthesiol Clin North America 2003;21(1):87–98.

    Article  PubMed  Google Scholar 

  11. Cohen SE. The aspiration syndrome. Clin Obstet Gynaecol 1982;9(2):235–254.

    PubMed  CAS  Google Scholar 

  12. Carp H, Jayaram A, Stoll M. Ultrasound examination of the stomach contents of parturients. Anesth Analg 1992;74(5):683–687.

    Article  PubMed  CAS  Google Scholar 

  13. Cheek TG, Gutsche BB. Pulmonary aspiration of gastric contents. In: Hughes SC, Levinson G, Rosen MA, editors. Shnider and Levinson's Anesthesia for Obstetrics. 4th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2002 p. 391–405.

    Google Scholar 

  14. Johnson MD, Ostheimer GW. Airway management in obstetric patients. Semin Anesth 1992; XI(1):1–12.

    Google Scholar 

  15. Morgan BM, Magni V, Goroszenuik T. Anesthesia for emergency cesarean section. Br J Obstet Gynaecol 1990;97:420–424.

    Article  PubMed  CAS  Google Scholar 

  16. Practice guidelines for management of the difficult airway: an updated report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway. Anesthesiology 2003;98(5):1269–1277.

    Google Scholar 

  17. Levine RJ, Lam C, Qian C et al. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. N Engl J Med 2006;355(10):992–1005.

    Article  PubMed  CAS  Google Scholar 

  18. Venkatesha S, Toporsian M, Lam C et al. Soluble endoglin contributes to the pathogenesis of preeclampsia. Nat Med 2006;12(6):642–649.

    Article  PubMed  CAS  Google Scholar 

  19. Lam C, Lim KH, Karumanchi SA. Circulating angiogenic factors in the pathogenesis and prediction of preeclampsia. Hypertension 2005;46(5):1077–1085.

    Article  PubMed  CAS  Google Scholar 

  20. Levine RJ, Maynard SE, Qian C et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004;350(7):672–683.

    Article  PubMed  CAS  Google Scholar 

  21. Ezri T, Szmuk P, Evron S, Geva D, Hagay Z, Katz J. Difficult airway in obstetric anesthesia: a review. Obstet Gynecol Surv 2001;56(10):631–641.

    Article  PubMed  CAS  Google Scholar 

  22. Heller PJ, Scheider EP, Marx GF. Pharyngolaryngeal edema as a presenting symptom in preeclampsia. Obstet Gynecol 1983;62(4):523–525.

    PubMed  CAS  Google Scholar 

  23. Pritchard JA. Severe preeclampsia with pharyngolaryngeal edema. Obstet Gynecol 1984;64(1):146–147.

    PubMed  CAS  Google Scholar 

  24. Rasmussen GE, Malinow AM. Toward reducing maternal mortality: the problem airway in obstetrics. Int Anesthesiol Clin 1994;32(2):83–101.

    PubMed  CAS  Google Scholar 

  25. Ramanathan J, Bennett K. Pre-eclampsia: fluids, drugs, and anesthetic management. Anesthesiol Clin North America 2003;21(1):145–163.

    Article  PubMed  Google Scholar 

  26. Rocke DA, Scoones GP. Rapidly progressive laryngeal oedema associated with pregnancy-aggravated hypertension. Anaesthesia 1992;47(2):141–143.

    Article  PubMed  CAS  Google Scholar 

  27. Perlow JH, Kirz DS. Severe preeclampsia presenting as dysphonia secondary to uvular edema. A case report. J Reprod Med 1990;35(11):1059–1062.

    CAS  Google Scholar 

  28. Hood DD, Dewan DM. Anesthetic and obstetric outcome in morbidly obese parturients. Anesthesiology 1993;79(6):1210–1218.

    Article  PubMed  CAS  Google Scholar 

  29. Kaiser PS, Kirby RS. Obesity as a risk factor for cesarean in a low-risk population. Obstet Gynecol 2001;97(1):39–43.

    Article  PubMed  CAS  Google Scholar 

  30. Pathi A, Esen U, Hildreth A. A comparison of complications of pregnancy and delivery in morbidly obese and non-obese women. J Obstet Gynaecol 2006;26(6):527–530.

    Article  PubMed  CAS  Google Scholar 

  31. Saravanakumar K, Rao SG, Cooper GM. The challenges of obesity and obstetric anaesthesia. Curr Opin Obstet Gynecol 2006;18(6):631–635.

    Article  PubMed  Google Scholar 

  32. Endler GC, Mariona FG, Sokol RJ, Stevenson LB. Anesthesia-related maternal mortality in Michigan, 1972 to 1984. Am J Obstet Gynecol 1988;159(1):187–193.

    PubMed  CAS  Google Scholar 

  33. Adams JP, Murphy PG. Obesity in anaesthesia and intensive care. Br J Anaesth 2000; 85(1):91–108.

    Article  PubMed  CAS  Google Scholar 

  34. Cooper GM, McClure JH. Maternal deaths from anaesthesia. An extract from Why Mothers Die 2000–2002, the Confidential Enquiries into Maternal Deaths in the United Kingdom: Chapter 9: Anaesthesia. Br J Anaesth 2005;94(4):417–423.

    Article  PubMed  CAS  Google Scholar 

  35. Chadwick HS. Obstetric anesthesia closed claims update II. Anesthesiol Newsl 1999;63:1–6.

    Google Scholar 

  36. Bandi VD, Munnur U, Matthay MA. Acute lung injury and acute respiratory distress syndrome in pregnancy. Crit Care Clin 2004;20(4):577–607.

    Article  PubMed  Google Scholar 

  37. Anesthesia for emergency deliveries. ACOG committee opinion: committee on obstetrics: maternal and fetal medicine. Number 104 – March 1992. Int J Gynaecol Obstet 1992;39(2):148.

    Google Scholar 

  38. Samsoon GL, Young JR. Difficult tracheal intubation: a retrospective study. Anaesthesia 1987;42(5):487–490.

    Article  PubMed  CAS  Google Scholar 

  39. Lyons G. Failed intubation. Six years' experience in a teaching maternity unit. Anaesthesia 1985;40(8):759–762.

    Article  PubMed  CAS  Google Scholar 

  40. Glassenberg R. General anesthesia and maternal mortality. Semin Perinatol 1991;15(5):386–396.

    PubMed  CAS  Google Scholar 

  41. Bucklin BA. Gerard W. Ostheimer “what's new in obstetric anesthesia” lecture. Anesthesiology 2006;104(4):865–871.

    Article  PubMed  Google Scholar 

  42. Han TH, Brimacombe J, Lee EJ, Yang HS. The laryngeal mask airway is effective (and probably safe) in selected healthy parturients for elective Cesarean section: a prospective study of 1067 cases. Can J Anaesth 2001;48(11):1117–1121.

    Article  PubMed  CAS  Google Scholar 

  43. Stamer UM, Messerschmidt A, Wulf H, Hoeft A. Equipment for the difficult airway in obstetric units in Germany. J Clin Anesth 2000;12(2):151–156.

    Article  PubMed  CAS  Google Scholar 

  44. Gataure PS, Hughes JA. The laryngeal mask airway in obstetrical anaesthesia. Can J Anaesth 1995;42(2):130–133.

    Article  PubMed  CAS  Google Scholar 

  45. Niazi A, Cummins E, Walsh K. Difficult airway equipment in obstetric units in the republic of Ireland: results of a national survey. Eur J Anaesthesiol 2004;21(11):861–863.

    PubMed  CAS  Google Scholar 

  46. Awan R, Nolan JP, Cook TM. Use of a ProSeal laryngeal mask airway for airway maintenance during emergency Caesarean section after failed tracheal intubation. Br J Anaesth 2004;92(1):144–146.

    Article  PubMed  CAS  Google Scholar 

  47. Keller C, Brimacombe J, Lirk P, Puhringer F. Failed obstetric tracheal intubation and postoperative respiratory support with the ProSeal laryngeal mask airway. Anesth Analg 2004;98(5):1467–1470, table.

    Article  PubMed  Google Scholar 

  48. Cook TM, Brooks TS, Van der WJ, Clarke M. The Proseal LMA is a useful rescue device during failed rapid sequence intubation: two additional cases. Can J Anaesth 2005;52(6):630–633.

    Article  PubMed  Google Scholar 

  49. Sharma B, Sahai C, Sood J, Kumra VP. The ProSeal laryngeal mask airway in two failed obstetric tracheal intubation scenarios. Int J Obstet Anesth 2006;15(4):338–339.

    Article  PubMed  CAS  Google Scholar 

  50. Bullingham A. Use of the ProSeal laryngeal mask airway for airway maintenance during emergency Caesarean section after failed intubation. Br J Anaesth 2004;92(6):903.

    Article  PubMed  CAS  Google Scholar 

  51. Minville V, N'guyen L, Coustet B, Fourcade O, Samii K. Difficult airway in obstetric using Ilma-Fastrach. Anesth Analg 2004;99(6):1873.

    PubMed  Google Scholar 

  52. Gonzalez GG, Marenco de la Fuente ML, Bertomeu CM. Fastrach mask to resolve a difficult airway during emergency cesarean section. Rev Esp Anestesiol Reanim 2005; 52(1):56–57.

    Google Scholar 

  53. Wissler RN. The esophageal-tracheal Combitube. Anesthesiol Rev 1993;20(4):147–152.

    PubMed  CAS  Google Scholar 

  54. Munnur U, Karnad DR, Bandi VD et al. Critically ill obstetric patients in an American and an Indian public hospital: comparison of case-mix, organ dysfunction, intensive care requirements, and outcomes. Intensive Care Med 2005;31(8):1087–1094.

    Article  PubMed  Google Scholar 

  55. Hazelgrove JF, Price C, Pappachan VJ, Smith GB. Multicenter study of obstetric admissions to 14 intensive care units in southern England. Crit Care Med 2001;29(4):770–775.

    Article  PubMed  CAS  Google Scholar 

  56. Jenkins TM, Troiano NH, Graves CR, Baird SM, Boehm FH. Mechanical ventilation in an obstetric population: characteristics and delivery rates. Am J Obstet Gynecol 2003;188(2):549–552.

    Article  PubMed  Google Scholar 

  57. Ben LD, Daouas N, Ben JK, Slama A, Jegham H. Maternal emergencies requiring controlled ventilation: epidemiology and prognosis. J Gynecol Obstet Biol Reprod (Paris) 2002;31(3):256–260.

    Google Scholar 

  58. Reddy R, Evans E, Khoo O, Allen MB. Pregnancy in kyphoscoliosis: benefit of non-invasive ventilatory support. J Obstet Gynaecol 2005;25(3):267–268.

    Article  PubMed  CAS  Google Scholar 

  59. Diaz-Lobato S, Gomez Mendieta MA, Moreno Garcia MS, Mayoralas-Alises S, Arpa Gutierrez FJ. Two full-term pregnancies in a patient with mitochondrial myopathy and chronic ventilatory insufficiency. Respiration 2005;72(6):654–656.

    PubMed  Google Scholar 

  60. Warren J, Sharma SK. Ventilatory support using bilevel positive airway pressure during neuraxial blockade in a patient with severe respiratory compromise. Anesth Analg 2006;102(3):910–911.

    Article  PubMed  Google Scholar 

  61. Kahler CM, Hogl B, Habeler R et al. Management of respiratory deterioration in a pregnant patient with severe kyphoscoliosis by non-invasive positive pressure ventilation. Wien Klin Wochenschr 2002;114(19–20):874–877.

    PubMed  Google Scholar 

  62. Cole DE, Taylor TL, McCullough DM, Shoff CT, Derdak S. Acute respiratory distress syndrome in pregnancy. Crit Care Med 2005;33(10 Suppl):S269–S278.

    Article  PubMed  Google Scholar 

  63. Hess D, Kacmarek R. Essentials of Mechanical Ventilation. First ed. McGraw-Hill: 1996.

    Google Scholar 

  64. Hess D, Branson R. New modes of ventilation. In: Hill N, Levy M, editors. Ventilator Management Strategies for Critical Care. New York: Marcel Dekker, Inc; 2001 p. 171–211.

    Google Scholar 

  65. Campbell LA, Klocke RA. Implications for the pregnant patient. Am J Respir Crit Care Med 2001;163(5):1051–1054.

    PubMed  CAS  Google Scholar 

  66. Walker AM, Oakes GK, Ehrenkranz R, McLaughlin M, Chez RA. Effects of hypercapnia on uterine and umbilical circulations in conscious pregnant sheep. J Appl Physiol 1976;41(5 Pt. 1):727–733.

    PubMed  CAS  Google Scholar 

  67. ARDS Net. ARMA protocol. ARDS Net 2007;2-14-2007. Ref Type: Electronic Citation.

    Google Scholar 

  68. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000;342(18):1301–1308.

    Article  Google Scholar 

  69. Contreras G, Gutierrez M, Beroiza T et al. Ventilatory drive and respiratory muscle function in pregnancy. Am Rev Respir Dis 1991;144(4):837–841.

    Article  PubMed  CAS  Google Scholar 

  70. Baldwin GR, Moorthi DS, Whelton JA, MacDonnell KF. New lung functions and pregnancy. Am J Obstet Gynecol 1977;127(3):235–239.

    PubMed  CAS  Google Scholar 

  71. Crapo RO. Normal cardiopulmonary physiology during pregnancy. Clin Obstet Gynecol 1996;39(1):3–16.

    Article  PubMed  CAS  Google Scholar 

  72. Morishima HO, Daniel SS, Adamsons K, Jr., James LS. Effects of positive pressure ventilation of the mother upon the acid-base state of the fetus. Am J Obstet Gynecol 1965;93:269–273.

    PubMed  CAS  Google Scholar 

  73. Motoyama EK, Rivard G, Acheson F, Cook CD. Adverse effect of maternal hyperventilation on the fetus. Lancet 1966;1(7432):286–288.

    Article  PubMed  CAS  Google Scholar 

  74. Lumley J, Wood C. Effect of changes in maternal oxygen and carbon dioxide tensions on the fetus. Clin Anesth 1974;10(2):121–137.

    PubMed  CAS  Google Scholar 

  75. Behrman RE, Parer JT, Novy MJ. Acute maternal respiratory alkalosis (hyperventilation) in the pregnant rhesus monkey. Pediatr Res 1967;1(5):354–363.

    Article  PubMed  CAS  Google Scholar 

  76. Bruce DA. Effects of hyperventilation on cerebral blood flow and metabolism. Clin Perinatol 1984;11(3):673–680.

    PubMed  CAS  Google Scholar 

  77. Marino P. Principles of mechanical ventilation. In: Marino P, editor. The ICU Book. Second ed. Baltimore, MD: Williams & Wilkins; 1997 p. 421–433.

    Google Scholar 

  78. Caplan RA, Posner KL, Ward RJ, Cheney FW. Adverse respiratory events in anesthesia: a closed claims analysis. Anesthesiology 1990;72(5):828–833.

    Article  PubMed  CAS  Google Scholar 

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Munnur, U., Bandi, V.D., Gropper, M.A. (2009). Airway Management and Mechanical Ventilation in Pregnancy. In: Rosene-Montella, K., Bourjeily, G. (eds) Pulmonary Problems in Pregnancy. Respiratory Medicine. Humana Press. https://doi.org/10.1007/978-1-59745-445-2_23

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