Abstract
Ancient records of diabetes generally contain no reference to its complications involving the nervous system. A few rare exceptions describing autonomic and painful neuropathies are all coming from the Orient. It was not until the 18th century that Western physicians started studying diabetes and its complications. Eventually, the works of the 19th century (de Calvi, Pavy) clearly established the link between diabetes mellitus and diabetic neuropathies. The epochal discovery of insulin in 1921 triggered a wide interest and more systematic approach to research of diabetic complications, leading to S. Fagerberger’s conclusion that many of them share the underlying microvascular pathology.
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Skljarevski, V. (2007). Historical Aspects of Diabetic Neuropathies. In: Veves, A., Malik, R.A. (eds) Diabetic Neuropathy. Clinical Diabetes. Humana Press. https://doi.org/10.1007/978-1-59745-311-0_1
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DOI: https://doi.org/10.1007/978-1-59745-311-0_1
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