Abstract
Usage of botulinum toxin (BTX) for cosmetic treatment was approved by the Food and Drug Administration (FDA) only a few years ago and already Botox® has become a household name. Some people have substituted Tupperware® parties for Botox parties. Few, however, are aware of the fascinating history of Botox and its many therapeutic uses.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Erbguth FJ. Historical notes on botulism, Clostridium botulinum, botulinum toxin, and the idea of the therapeutic use of the toxin. Mov Dis 2004;19:S2–S6.
Erbguth FJ, Naumann M. Historical aspects of botulinum toxin: Justinus Kerner (1786–1862) and the “sausage poison.” Neurology 1999;53:1850.
Kedlaya D. Botulinum toxin: overview. Available from: http://www.emedicine.com/pmr/topic216. htm#section~author_information. Accessed Jan. 23, 2006.
Garland Science. Botulinum toxin: core materials. Available from: http://www.garlandscience.com/ textbooks/cbl/CoreMaterials/timeline.html. Accessed: Jan. 22, 2006.
Meriggioli MN, Howard JF Jr., Harper CM. Neuromuscular Junction Disorders, Diagnosis and Treatment. New York, NY: Marcel Dekker; 2003.
Blasi J, Chapman ER, Link E, et al. Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25. Nature 1993;365:160–163.
Jankovic J, Brin MF. Botulinum toxin: historical perspective and potential new indications. Muscle Nerve Suppl 1997;6:S129–S145.
Brin MF. Botulinum toxin: chemistry, pharmacology, toxicity, and immunology. Muscle Nerve Suppl 1997;6:S146–S168.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2007 Humana Press Inc.
About this chapter
Cite this chapter
Meyler, Z., Cooper, G. (2007). History and Mechanism of Action. In: Cooper, G. (eds) Therapeutic Uses of Botulinum Toxin. Humana Press. https://doi.org/10.1007/978-1-59745-247-2_1
Download citation
DOI: https://doi.org/10.1007/978-1-59745-247-2_1
Publisher Name: Humana Press
Print ISBN: 978-1-58829-914-7
Online ISBN: 978-1-59745-247-2
eBook Packages: MedicineMedicine (R0)