Abstract
Major complications related to atrial fibrillation (AF) ablation have been reported in 3% to 6% of procedures. These include pulmonary vein stenosis, thromboembolic events, phrenic and recurrent laryngeal nerve injury, cardiac perforation and tamponade, and atrio—esophageal fistula. A better understanding of the pathophysiology of these events has decreased the current incidence to 1% to 2%. Formal evaluation of procedural effi cacy includes assessment of AF-free survival, although the format and extent of postprocedural rhythm evaluation and the signifi cance of asymptomatic AF remain controversial. Consensus guidelines for defi ning successful AF ablation are under development.
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References
1. Allessie MA RP, Brugada J, Smeets JLRM, Penn OC, Kirchof CJHS. Pathophysiology of atrial fibrillation. In: Zipes DP, ed. Cardiac electrophysiology: from cell to bedside. Philadelphia, Pa: Saunders; 1990:548–599.
2. Haissaguerre M JP, Shah DC, Takahashi A, Hocini M, Quiniou G, LeMouroux A, Le Metayer P, Clementy J. Spontaneous initiation of atrial fibrillation by ectopic beats originating from pulmonary veins. N Engl J Med. 1998;339:659–666.
3. Haissaguerre M JP, Shah DC, Garrigue S, Takahashi A, Lavergne T,, Hocini M PJ, Roudaut R, Clementy J. Electrophysiological end point for catheter ablation of atrial fibrillation initiated from multiple pulmonary venous foci. Circulation. 2000;101:1409–1417.
4. Chen SA HM, Tai CT, Tsai CF, Prakash VS, Yu WC, Hsu TL, Ding YA, Chang MS. Initiation of atrial fibrillation by ectopic beats originating from the pulmonary veins: electrophysiologic characteristics, pharmacological responses, and effects of radiofrequency ablation. Circulation. 1999;100:1879–1886.
5. Jais P HM, Shah DC, Chouari S, Gencel L, Hocini M, Clementy J. A focal source of atrial fibrillation treated by discrete radiofrequency ablation. Circulation. 1997;95:572–576.
6. Oral H, Knight BP, Tada H, et al. Pulmonary vein isolation for paroxysmal and persistent atrial fibrillation. Circulation. 2002;105:1077–1081.
7. Pappone C OG, Rosanio S, Vicedomini G, Tocchi M, Gugliotta F, Salvati A, Dicandia C, Calabro MP, Mazzone P, Ficarra E, De Gioia C, Gulletta S NS, Santinelli V, Benussi S, Alfieri O. Atrial electroanatomic remodeling after circumferential radiofrequency pulmonary vein ablation: efficacy of an anatomic approach in a large cohort of patients with atrial fibrillation. Circulation. 2001;104:2539–2544.
8. Pappone C RS, Oreto G, Tocchi M, Gugliotta F, Vicedomini G, Salvati A, Dicandia C, Mazzone P, Santinelli V, Gulletta S, Cherchia S. Circumferential radiofrequency ablation of pulmonary vein ostia: a new anatomic approach for curing atrial fibrillation. Circulation. 2000;102:2619–2628.
9. Kanagaratnam L TG, Schweikert R, Pavia S, Bash D, Beheiry, S LM, Niebauer M, Saliba W, Chung M, Tchou P, Natale A. Empirical pulmonary vein isolation in patients with chronic atrial fibrillation using a three-dimensional nonfluoroscopic mapping system: long-term follow-up. Pacing Clin Electrophysiol. 2001;24:1774–1779.
10. Cappato R CH, Chen SA, et al. Worldwide survey on the methods, efficacy, and safety of catheter ablation for human atrial fibrillation. Circulation. 2005;111:1100–1105.
11. Taylor G, Kay GN, Zheng X, et al. Pathological effects of extensive radiofrequency energy applications in the pulmonary veins in dogs. Circulation. 2000;101:1736.
12. Purerfellner H, Martinek M. Pulmonary vein stenosis following catheter ablation of atrial fibrillation. Curr Opin Cardiol. 2005;20:484–490.
Packer D. Linear ablation for atrial fibrillation. Armonk, NY: Futura; 2001.
14. Gerstenfeld EPGP, Sparks PB, Hattori K, Lesh MD. Clinical outcome after radiofrequency catheter ablation of focal atrial fibrillation triggers. J Cardiovasc Electrophysiol. 2001;12:900–908.
15. Packer DLAS, Monahan KH, Shen WK, Rea RF, Hammill SC. Progression of pulmonary vein stenosis in patients following focal atrial fibrillation ablation. Circulation. 2001;104(suppl II):II-461.
16. Leite L AS, Hammill SC, Friedman PA, Munger TM, Shen WK, Packer DL. Clinical and electrophysiological predictors of pulmonary vein stenosis following radiofrequency catheter ablation for atrial fibrillation. Pacing Clin Electrophysiol. 2002;25:559.
17. Yu WC HT, Tai CT, Tsai CF, Hsieh MH, Lin WS, Lin YK, Tsao HM, Ding YA, Chang MS, Chen SA. Acquired pulmonary vein stenosis after radiofrequency catheter ablation of paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol. 2001;12:887–892.
18. Ernst S QF, Goya M, Menke K, Vogtmann T, Antz M, Kuck KH. Does lower RFC temperature to avoid PV stenosis cause more arrhythmic relapse after selective PV isolation. Pacing Clin Electrophysiol. 2002;25:638.
19. Saad EB RA, Saad CP, Martin DO, Bhargava M, Erciyes D, Bash D, Williams-Andrews M, Beheiry S, Marrouche NF, Adams J, Pisano E, Fanelli R, Potenza D, Raviele A, Bonso A, Themistoclakis S, Brachmann J, Saliba WI, Schweikert RA, Natale A. Pulmonary vein stenosis after radiofrequency ablation of atrial fibrillation: functional characterization, evolution, and influence of the ablation strategy. Circulation. 2003;108:3102–3107.
20. Saad EB MN, Saad CP, et al. Pulmonary vein stenosis after catheter ablation of atrial fibrillation: emergence of a new clinical syndrome. Ann Intern Med. 2003;138:634.
21. Packer DL KP, Munger TM, et al. Clinical presentation, investigation, and management of pulmonary vein stenosis complicating ablation for atrial fibrillation. Circulation. 2005;111:546.
22. Purerfellner H CR, Aichinger J, et al. Pulmonary vein stenosis by ostial irrigated-tip ablation: incidence, time course, and prediction. J Cardiovasc Electrophysiol. 2003;14:158–164.
23. Qureshi A, Prieto LR, Latson LA, et al. Transcatheter angioplasty for acquired pulmonary vein stenosis after radiofrequency ablation. Circulation. 2003;108:1336.
24. Dill T, Neumann, T, Ekinci, O, et al. Pulmonary vein diameter reduction after radiofrequency catheter ablation for paroxysmal atrial fibrillation evaluated by contrastenhanced three-dimensional magnetic resonance imaging. Circulation. 2003;107:845.
25. Kluge A, Dill T, Ekinci O, et al. Decreased pulmonary perfusion in pulmonary vein stenosis after radiofrequency ablation: assessment with dynamic magnetic resonance perfusion imaging. Chest. 2004;126:428.
26. Arentz T, Weber R, Jander N, et al. Pulmonary haemodynamics at rest and during exercise in patients with significant pulmonary vein stenosis after radiofrequency catheter ablation for drug resistant atrial fibrillation. Eur Heart J. 2005;26:1410.
27. Gillinov AM, Pettersson G, Rice TW. Esophageal injury during radiofrequency ablation for atrial fibrillation. J Thorac Cardiovasc Surg. 2001;122(6):1239–1240.
28. Doll N, Borger MA, Fabricius A, et al. Esophageal perforation during left atrial radiofrequency ablation: Is the risk too high? J Thorac Cardiovasc Surg. 2003;125(4):836–842.
29. Sonmez B, Demirsoy E, Yagan N, et al. A fatal complication due to radiofrequency ablation for atrial fibrillation: atrio-esophageal fistula. Ann Thorac Surg. Jul 2003;76(1):281–283.
30. Pappone C, Oral H, Santinelli V, et al. Atrio-esophageal fistula as a complication of percutaneous transcatheter ablation of atrial fibrillation. Circulation. 2004;109(22):2724–2726.
31. Scanavacca MI, D'Avila A, Parga J, et al. Left atrial-esophageal fistula following radiofrequency catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2004;15(8):960–962.
32. Dagres N, Kottkamp H, Piorkowski K, Doll N, Mohr F, Horlitz M, Kremastinos D, Hindricks G. Rapid detection and successful treatment of esophageal perforation after radiofrequency ablation of atrial fibrillation: lessons from five cases. J Cardiovasc Electrophysiol. 2006;17(11):1213–1215.
33. Cummings JE, Schweikert RA, Saliba WI, Burkhardt JD, Kilikaslan F, Saad E, Natale A. Atrial-esophageal fistulas after radiofrequency ablation. Ann Int Med. 2006;144(8):572–574.
34. Lemola K, Sneider M, Desjardins B, et al. Computed tomographic analysis of the anatomy of the left atrium and the esophagus: implications for left atrial catheter ablation. Circulation. 2004;110(24):3655–3660.
35. Ho SY, Sanchez-Quintana D, Cabrera JA, et al. Anatomy of the left atrium: implications for radiofrequency ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 1999;10(11):1525–1533.
36. Sanchez-Quintana D, Cabrera JA, Climent V, et al. Anatomic relations between the esophagus and left atrium and relevance for ablation of atrial fibrillation. Circulation. 2005;112(10):1400–1405.
37. Damore LJ 2nd, Rantis PC, Vernava AM 3rd, et al. Colonoscopic perforations. Etiology, diagnosis, and management. Dis Colon Rectum. 1996;39(11):1308–1314.
38. Bunch TJ, Nelson J, Foley T, et al. Temporary esophageal stenting allows healing of esophageal perforations following atrial fibrillation ablation procedures. J Cardiovasc Electrophysiol. 2006;17(4):435–439.
39. Wang SL, Ooi CG, Siu CW, et al. Endocardial visualization of esophageal-left atrial anatomic relationship by three-dimensional multidetector computed tomography “navigator imaging”. Pacing Clin Electrophysiol. 2006;29(5):502–508.
40. Cronin P, Sneider MB, Kazerooni EA, et al. MDCT of the left atrium and pulmonary veins in planning radiofrequency ablation for atrial fibrillation: a how-to guide. AJR Am J Roentgenol. 2004;183(3):767–778.
41. Sosa E, Scanavacca M. Left atrial-esophageal fistula complicating radiofrequency catheter ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2005;16(3):249–250.
42. Yamada T, Murakami Y, Okada T, et al. Usefulness of esophageal leads for determining the strategy of pulmonary vein ablation to avoid complications associated with the esophagus. Am J Cardiol. 2006;97(10):1494–1497.
43. Han J, Good E, Morady F, et al. Images in cardiovascular medicine. Esophageal migration during left atrial catheter ablation for atrial fibrillation. Circulation. 2004;110(24):e528.
44. Dickfeld T, Calkins H, Zviman M, et al. Anatomic stereotactic catheter ablation on three-dimensional magnetic resonance images in real time. Circulation. 2003;108(19):2407–2413.
45. Yamane T, Matsuo S, Date T, et al. Visualization of the esophagus throughout left atrial catheter ablation for atrial fibrillation. J Cardiovasc Electrophysiol. 2006;17(1):105.
46. Redfearn DP, Trim GM, Skanes AC, et al. Esophageal temperature monitoring during radiofrequency ablation of atrial fibrillation. J Cardiovasc Electrophysiol. 2005;16(6):589–593.
47. Kottkamp H, Piorkowski C, Tanner H, et al. Topographic variability of the esophageal left atrial relation influencing ablation lines in patients with atrial fibrillation. J Cardiovasc Electrophysiol. 2005;16(2):146–150.
48. Oral H, Chugh A, Ozaydin M, Good E, Fortino J, Sankaran S, Reich S, Igic P, Elmouchi D, Tschopp D, Wimmer A, Dey S, Crawford T, Pelosi F Jr, Jongnarangsin K, Bogun F, Morady F. Risk of thromboembolic events after percutaneous left atrial radiofrequency ablation of atrial fibrillation. Circulation. 2006;114(8):759–765.
49. Ren JF, Marchlinski FE, Callans DJ. Left atrial thrombus associated with ablation for atrial fibrillation: identification with intracardiac echocardiography. J Am Coll Cardiol. 2004;43(10):1861–1867.
50. Lundqvist C, Olsson S, Varnauskas E. Transeptal left heart catheterization: a review of 278 studies. Clin Cardiol. 1986;9:21–26.
51. Zhou L, Keane D, Reed G, et al. Thromboembolic complications of cardiac radiofrequency catheter ablation: a review of the reported incidence, pathogenesis and current research directions. J Cardiovasc Electrophysiol. 1999;10(4):611–620.
52. Kok LC, Mangrum JM, Haines DE, et al. Cerebrovascular complication associated with pulmonary vein ablation. J Cardiovasc Electrophysiol. 2002;13(8):764–767.
53. Epstein MR, Knapp LD, Martindill M, et al. Embolic complications associated with radiofrequency catheter ablation. Atakr Investigator Group. Am J Cardiol. 1996;77(8):655–658.
54. Cauchemez B, Extramiana F, Cauchemez S, et al. High-flow perfusion of sheaths for prevention of thromboembolic complications during complex catheter ablation in the left atrium. J Cardiovasc Electrophysiol. 2004;15(3):276–283.
55. Dorwarth U, Fiek M, Remp T, Reithmann C, Dugas M, Steinbeck G, Hoffmann E. Radiofrequency catheter ablation: different cooled and noncooled electrode systems induce specific lesion geometries and adverse effects profiles. Pacing Clin Electrophysiol. 2003;26(7 pt 1):1438–1445.
56. Lee DS, Dorian P, Downar E, et al. Thrombogenicity of radiofrequency ablation procedures: what factors influence thrombin generation? Europace. 2001;3(3):195–200.
57. Manolis AS, Maounis T, Vassilikos V, et al. Pretreatment with antithrombotic agents during radiofrequency catheter ablation: a randomized comparison of aspirin vs ticlopidine. J Cardiovasc Electrophysiol. 1998;9(11):1144–1151.
58. Anfinsen OG, Gjesdal K, Brosstad F, et al. The activation of platelet function, coagulation, and fibrinolysis during radiofrequency catheter ablation in heparinized patients. J Cardiovasc Electrophysiol. 1999;10(4):503–512.
59. Dorbala S, Cohen AJ, Hutchinson LA, et al. Does radiofrequency ablation induce a prethrombotic state? Analysis of coagulation system activation and comparison to electrophysiologic study. J Cardiovasc Electrophysiol. 1998;9(11):1152–1160.
60. Lickfett L, Hackenbroch M, Lewalter T, et al. Cerebral diffusion-weighted magnetic resonance imaging: a tool to monitor the thrombogenicity of left atrial catheter ablation. J Cardiovasc Electrophysiol. 2006;17(1):1–7.
61. Schaefer PW, Grant PE, Gonzalez RG. Diffusion-weighted MR imaging of the brain. Radiology. 2000;217(2):331–345.
62. Raja PV, Blumenthal JA, Doraiswamy PM. Cognitive deficits following coronary artery bypass grafting: prevalence, prognosis, and therapeutic strategies. CNS Spectr. 2004;9(10):763–772.
63. Khairy P, Chauvet P, Lehmann J, et al. Lower incidence of thrombus formation with cryoenergy vs radiofrequency catheter ablation. Circulation. 2003;107(15):2045–2050.
64. Natale A, Pisano E, Shewchik J, et al. First human experience with pulmonary vein isolation using a through-the-balloon circumferential ultrasound ablation system for recurrent atrial fibrillation. Circulation. 2000;102(16):1879–1882.
65. Johnson SB, Seward J, DL P. Phased-array intracardiac echocardiography for guiding transeptal catheter placement: Utility and learning curve. Pacing Clin Electrophysiol. 2002;25(pt 1):402–407.
66. Asirvatham SJ, Johnson SB, DL P. Utility of intracardiac ultrasound (ICUS) in guiding circumferential pulmonary venous ablation with a tandem balloon catheter. Pacing Clin Electrophysiol. 1999;22:822.
67. Wazni OM, Rossillo A, Marrouche NF, et al. Embolic events and char formation during pulmonary vein isolation in patients with atrial fibrillation: impact of different anticoagulation regimens and importance of intracardiac echo imaging. J Cardiovasc Electrophysiol. 2005;16(6):576–581.
68. Rumbak MJ, Chokshi SK, Abel N, et al. Left phrenic nerve paresis complicating catheter radiofrequency ablation for Wolff—Parkinson—White syndrome. Am Heart J. 1996;132(6):1281–1285.
69. Durante-Mangoni E, Del Vecchio D, Ruggiero G. Right diaphragm paralysis following cardiac radiofrequency catheter ablation for inappropriate sinus tachycardia. Pacing Clin Electrophysiol. 2003;26(3):783–784.
70. Lee BK, Choi KJ, Kim J, et al. Right phrenic nerve injury following electrical disconnection of the right superior pulmonary vein. Pacing Clin Electrophysiol. 2004;27(10):1444–1446.
71. Sacher F, Monahan KH, Thomas SP, Davidson N, Adragao P, Sanders P, Hocini M, Takahashi Y, Rotter M, Rostock T, Hsu LF, Clementy J, Haissaguerre M, Ross DL, Packer DL, Jais P. Phrenic nerve injury after atrial fibrillation catheter ablation: characterization and outcome in a multicenter study. J Am Coll Cardiol. 2006;47(12):2498–2503.
72. Pai RK, Boyle NG, Child JS, et al. Transient left recurrent laryngeal nerve palsy following catheter ablation of atrial fibrillation. Heart Rhythm. 2005;2(2):182–184.
73. Sanchez-Quintana D, Cabrera JA, Climent V, et al. How close are the phrenic nerves to cardiac structures? Implications for cardiac interventionalists. J Cardiovasc Electrophysiol. 2005;16(3):309–313.
Gray H. Anatomy of the human body. 20th ed. Lippincott Williams and Wilkins.
75. Haines DE, Watson DD. Tissue heating during radiofrequency catheter ablation: a thermodynamic model and observations in isolated perfused and superfused canine right ventricular free wall. Pacing Clin Electrophysiol. 1989;12(6):962–976.
76. Tsong TY, Su ZD. Biological effects of electric shock and heat denaturation and oxidation of molecules, membranes, and cellular functions. Ann N Y Acad Sci. 1999;888:211–232.
77. Ge YZ, Shao PZ, Goldberger J, et al. Cellular electrophysiological changes induced in vitro by radiofrequency current: comparison with electrical ablation. Pacing Clin Electrophysiol. 1995;18(2):323–333.
78. Bunch TJ, Bruce GK, Mahapatra S, et al. Mechanisms of phrenic nerve injury during radiofrequency ablation at the pulmonary vein orifice. J Cardiovasc Electrophysiol. 2005;16(12):1318–1325.
79. Sarabanda AV, Johnson SB, Bunch TJ, et al. Determinants of successful circumferential isolation of pulmonary veins using a novel cryothermal balloon ablation system in a canine model. Heart Rhythm. 2004;1:239.
80. Su W, Johnson SB, DL P. Collateral damage from circumferential laser energy ablation of pulmonary veins. Eur Heart J. 2002;23:522.
81. Antz M, Chun KR, Ouyang F, Kuck KH. Ablation of atrial fibrillation in humans using a balloon-based ablation system: identification of the site of phrenic nerve damage using pacing maneuvers and CARTO. J Cardiovasc Electrophysiol. 2006;17(11):1242–1245.
82. Saliba W, Wilber D, Packer D, et al. Circumferential ultrasound ablation for pulmonary vein isolation: analysis of acute and chronic failures. J Cardiovasc Electrophysiol. 2002;13(10):957–961.
83. Lowe M, Peterson LM, KH, Asirvatham SJ, et al. Electroanatomical mapping to assess phrenic nerve proximity to superior vena cava and pulmonary vein ostia. Heart. 2004;90:24.
84. Chen SA, Chiang CE, Tai CT, et al. Complications of diagnostic electrophysiologic studies and radiofrequency catheter ablation in patients with tachyarrhythmias: an eight-year survey of 3,966 consecutive procedures in a tertiary referral center. Am J Cardiol. 1996;77(1):41–46.
85. Greene TO, Huang SK, Wagshal AB, et al. Cardiovascular complications after radiofrequency catheter ablation of supraventricular tachyarrhythmias. Am J Cardiol. 1994;74(6):615–617.
86. Hindricks G. The Multicentre European Radiofrequency Survey (MERFS): complications of radiofrequency catheter ablation of arrhythmias. The Multicentre European Radiofrequency Survey (MERFS) investigators of the Working Group on Arrhythmias of the European Society of Cardiology. Eur Heart J. 1993;14(12):1644–1653.
87. Scheinman MM. NASPE survey on catheter ablation. Pacing Clin Electrophysiol. 1995;18(8):1474–1478.
88. Bunch TJ, Asirvatham SJ, Friedman PA, et al. Outcomes after cardiac perforation during radiofrequency ablation of the atrium. J Cardiovasc Electrophysiol. 2005;16(11):1172–1179.
89. Hsu LF, Jais P, Hocini M, Sanders P, Scavee C, Sacher F, Takahashi Y, Rotter M, Pasquie JL, Clementy J, Haissaguerre M. Incidence and prevention of cardiac tamponade complicating ablation for atrial fibrillation. Pacing Clin Electrophysiol. 2005;28(suppl 1):S106–S109.
90. Bhargava M, Marrouche NF, Martin DO, Schweikert RA, Saliba W, Saad EB, Bash D, Williams-Andrews M, Rossillo A, Erciyes D, Khaykin Y, Burkhardt JD, Joseph G, Tchou PJ, Natale A. Impact of age on the outcome of pulmonary vein isolation for atrial fibrillation using circular mapping technique and cooled-tip ablation catheter. J Cardiovasc Electrophysiol. 2004;15(1):8–13.
91. Asirvatham SJ, Holmes DR Jr. Transseptal catheterization: how do we get there from here—is it safe and in whose hands? J Cardiovasc Electrophysiol. 2005;16(6):566–567.
92. Hindricks G, Piorkowski C, Tanner H, Kobza R, Gerds-Li JH, Carbucicchio C, Kottkamp H. Perception of atrial fibrillation before and after radiofrequency catheter ablation: relevance of asymptomatic arrhythmia recurrence. Circulation. 2005;112(3):307–13.
93. Israel CW, Gronefeld G, Ehrlich JR, et al. Long-term risk of recurrent atrial fibrillation as documented by an implantable monitoring device: implications for optimal patient care. J Am Coll Cardiol. 2004;43(1):47–52.
94. Page RL, Tilsch TW, Connolly SJ, et al. Asymptomatic or “silent” atrial fibrillation: frequency in untreated patients and patients receiving azimilide. Circulation. 2003;107(8):1141–1145.
95. Savelieva I, Camm AJ. Clinical relevance of silent atrial fibrillation: prevalence, prognosis, quality of life, and management. J Interv Card Electrophysiol. 2000;4(2):369–382.
96. Humphries KH, Kerr CR, Connolly SJ, et al. New-onset atrial fibrillation: sex differences in presentation, treatment, and outcome. Circulation. 2001;103(19):2365–2370.
97. Senatore G, Stabile G, Bertaglia E, et al. Role of transtelephonic electrocardiographic monitoring in detecting short-term arrhythmia recurrences after radiofrequency ablation in patients with atrial fibrillation. J Am Coll Cardiol. 2005;45(6):873–876.
98. Vasamreddy CR, Dalal D, Dong J, Cheng A, Spragg D, Lamiy SZ, Meininger G, Henrikson CA, Marine JE, Berger R, Calkins H. Symptomatic and asymptomatic atrial fibrillation in patients undergoing radiofrequency catheter ablation. J Cardiovasc Electrophysiol. 2006;17(2):134–139.
99. Turco P, DE Simone A, LA Rocca V, Iuliano A, Capuano V, Astarita C, DI Napoli T, Messina V, Baldi S, Stabile G. Antiarrhythmic drug therapy after radiofrequency catheter ablation in patients with atrial fibrillation. Pacing Clin Electrophysiol. 2007;30(suppl 1):S112–S115.
100. Oral H, Veerareddy S, Good E, et al. Prevalence of asymptomatic recurrences of atrial fibrillation after successful radiofrequency catheter ablation. J Cardiovasc Electrophysiol. 2004;15(8):920–924.
101. Pappone C, Santinelli V, Manguso F, et al. Pulmonary vein denervation enhances long term benefit after circumferential ablation for paroxysmal atrial fibrillation. Circulation. 2004;109:327–334.
102. Gerstenfeld EP, Guerra P, Sparks PB, Hattori K, Lesh MD. Clinical outcome after radiofrequency catheter ablation of focal atrial fibrillation triggers. J Cardiovasc Electrophysiol. 2001;12:900–908.
103. Berkowitsch A, Neumann T, Kurzidim K, Reiner C, Kuniss M, Siemon G, Sperzel J, Pitschner HF. Comparison of generic health survey SF-36 and arrhythmia related symptom severity check list in relation to post-ablation recurrence. Europace. 2003;5:351–355.
104. Huang SK, Bharati S, Lev M, et al. Electrophysiologic and histologic observations of chronic atrioventricular block induced by closed-chest catheter desiccation with radiofrequency energy. Pacing Clin Electrophysiol. 1987;10(4 pt 1):805–816.
105. Huang SK, Graham AR, Wharton K. Radiofrequency catheter ablation of the left and right ventricles: anatomic and electrophysiologic observations. Pacing Clin Electrophysiol. 1988;11(4):449–459.
106. Wittkampf FH, Hauer RN, Robles de Medina EO. Control of radiofrequency lesion size by power regulation. Circulation. 1989;80(4):962–968.
107. Grubman E, Pavri BB, Lyle S, et al. Histopathologic effects of radiofrequency catheter ablation in previously infarcted human myocardium. J Cardiovasc Electrophysiol. 1999;10(3):336–342.
108. Tanno K, Kobayashi Y, Kurano K, et al. Histopathology of canine hearts subjected to catheter ablation using radiofrequency energy. Jpn Circ J. 1994;58(2):123–135.
109. Oral H, Knight BP, Ozaydin M, et al. Clinical significance of early recurrences of atrial fibrillation after pulmonary vein isolation. J Am Coll Cardiol. 2002;40(1):100–104.
110. Haissaguerre M, Shah DC, Jais P, et al. Electrophysiological breakthroughs from the left atrium to the pulmonary veins. Circulation. 2000;102(20):2463–2465.
111. Leite L, Bluhm CM, Monahan KH, et al. Long-term implications of early recurrence of atrial fibrillation following radiofrequency pulmonary vein isolation. Circulation. 2002;106:542.
112. Lee SH, Tai CT, Hsieh MH, Tsai CF, Lin YK, Tsao HM, Yu WC, Huang JL, Ueng KC, Cheng JJ, Ding YA, Chen SA. Predictors of early and late recurrence of atrial fibrillation after catheter ablation of paroxysmal atrial fibrillation. J Interv Cardiac Electrophysiol. 2004;10(3):221–226.
113. Bertaglia E, Stabile G, Senatore G, Zoppo F, Turco P, Amellone C, De Simone A, Fazzari M, Pascotto P. Predictive value of early atrial tachyarrhythmias recurrence after circumferential anatomical pulmonary vein ablation. Pacing Clin Electrophysiol. 2005;28(5):366–371.
114. Kottkamp H, Tanner H, Kobza R, Schirdewahn P, Dorszewski A, Gerds-Li JH, Carbucicchio C, Piorkowski C, Hindricks G. Time courses and quantitative analysis of atrial fibrillation episode number and duration after circular plus linear left atrial lesions: trigger elimination or substrate modification: early or delayed cure?. J Am Coll Cardiol. 2004;44(4):869–877.
115. Pappone C, Rosanio S, Augello G, et al. Mortality, morbidity, and quality of life after circumferential pulmonary vein ablation for atrial fibrillation: outcomes from a controlled nonrandomized long-term study. J Am Coll Cardiol. 2003;42(2):185–197.
116. Hsieh MH, Tai CT, Tsai CF, Lin WS, Lin YK, Tsao HM, Huang JL, Ueng KC, Yu WC, Chan P, Ding YA, Chang MS, Chen SA. Clinical outcome of very late recurrence of atrial fibrillation after catheter ablation of paroxysmal atrial fibrillation. J Cardiovasc Electrophysiol. 2003;14(6):598–601.
Cheema AA, Vasamreddy C, Dalal D, Henrickson C, Dong J, Spragg D, Cheng A, Nazarian S, Sinha S, Marine J, Berger R, Calkins H. Long term single procedure efficacy of catheter ablation of atrial fibrillation [abstract]. Heart Rhythm. 2006.
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Shapira, A., Wilber, D.J. (2008). Complications and Definition of Success. In: Natale, A., Jalife, J. (eds) Atrial Fibrillation. Contemporary Cardiology. Humana Press. https://doi.org/10.1007/978-1-59745-163-5_20
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