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Utility of Antifungal Susceptibility Testing and Clinical Correlations

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Book cover Interactions of Yeasts, Moulds, and Antifungal Agents

Abstract

In this chapter, we review the available published data addressing the clinical relevance of antifungal susceptibility test results. By far the most data exist to support the clinical relevance of AFST results for Candida against fluconazole, and these data suggest that the clinical utility of this information mirrors that put forward for antibacterial susceptibility testing. Clinical relevance has also been demonstrated for selected other antifungal agents against Candida and Cryptococcus spp. By contrast, little direct support for the clinical utility of AFST for moulds is available.

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Authors and Affiliations

  1. Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA, USA

    Daniel J. Diekema M.D.

  2. University of Iowa College of Public Health, Iowa City, IA, USA

    Daniel J. Diekema M.D. & Michael A. Pfaller M.D.

  3. Division of Clinical Microbiology, Department of Pathology, University of Iowa Carver College of Medicine, Iowa City, IA, USA

    Michael A. Pfaller M.D.

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  1. Daniel J. Diekema M.D.
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  2. Michael A. Pfaller M.D.
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Correspondence to Daniel J. Diekema M.D. .

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  1. Section of Clinical Microbiology, Department of Clinical Pathology, Cleveland Clinic, Euclid Ave. 9500, Cleveland, 44195, Ohio, USA

    Gerri S. Hall

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Diekema, D.J., Pfaller, M.A. (2012). Utility of Antifungal Susceptibility Testing and Clinical Correlations. In: Hall, G. (eds) Interactions of Yeasts, Moulds, and Antifungal Agents. Humana Press. https://doi.org/10.1007/978-1-59745-134-5_8

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