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Vasculitic Neuropathy

  • Michael Benatar

Abstract

The term “vasculitis” is used to describe a group of disorders that are characterized by the presence of a specific pathological finding—namely, inflammation and necrosis of blood vessel walls. Broadly speaking, this group of disorders may be classified into the systemic and nonsystemic (or localized) vasculitides. The systemic vasculitides encompass a broad range of diseases including (a) the vasculitides that result from direct infection of the blood vessel wall (e.g., syphilis, tuberculosis, and HIV infection), (b) the necrotizing vasculitides (e.g., polyarteritis nodosa, Churg-Strauss syndrome, Wegener’s granulomatosis, and the connective tissue disorders rheumatoid arthritis, systemic lupus erythematosis, and Sjogren’s syndrome), (c) the hypersensitivity vasculitides (e.g., druginduced cryoglobulinemia and malignancy) and (d) the giant cell arteritides (temporal arteritis and Takayasu’s arteritis). The nonsystemic vasculitides may affect either the central or the peripheral nervous system exclusively. In this chapter, we are concerned with the form of nonsystemic vasculitis that is confined to the peripheral nervous system as well as the systemic vasculitides in which the peripheral nervous system is also affected.

Keywords

Systemic Lupus Erythematosis Peripheral Nervous System Giant Cell Arteritis Systemic Vasculitis Neuromuscular Disease 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Humana Press Inc., Totowa, NJ 2006

Authors and Affiliations

  • Michael Benatar
    • 1
  1. 1.Department of NeurologyEmory University School of MedicineAtlanta

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