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Technique of Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA)

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Diagnostic and Therapeutic Procedures in Gastroenterology

Abstract

The advent of endoscopic ultrasound (EUS) and guided fine needle aspiration (FNA) has significantly altered the management of benign and malignant gastrointestinal, biliary-pancreatic and mediastinal disorders. Over the past two decades, EUS has evolved from being a diagnostic imaging modality to an interventional modality. Several evolving therapeutic applications are paving the way to previously unimaginable procedures such as transluminal endosurgery (Giovannini 2004). The technique of EUS-guided fine needle aspiration (EUS-FNA) forms the basis for all of the more invasive applications such as EUS-guided celiac ganglion neurolysis, pseudocyst drainage, pancreatic necrosectomy, periluminal abscess drainages, transgastric or transduodenal biliary-pancreatic drainage procedures etc (Giovannini 2004; Fritscher-ravns 2006).

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References

  • Adler DG, Conway JD, Coffie JM, Disario JA, Mishkin DS, Shah RJ, et al. EUS accessories. Gastrointest Endosc. 2007;66(6):1076–81.

    Article  PubMed  Google Scholar 

  • Al-Haddad M, Wallace MB, Woodward TA, Gross SA, Hodgens CM, Toton RD, et al. The safety of fine-needle aspiration guided by endoscopic ultrasound: a prospective study. Endoscopy. 2008;40(3):204–8.

    Article  PubMed  CAS  Google Scholar 

  • Al-Haddad M, Gill KR, Raimondo M, Woodward TA, Krishna M, Crook JE, Skarvinko LN, Jamil LH, Hasan M, Wallace MB. Safety and efficacy of cytology brushings versus standard fine-needle aspiration in evaluating cystic pancreatic lesions: a controlled study. Endoscopy 2009 Dec 7, Endoscopy. 2010;42(2):127–32.

    Google Scholar 

  • Binmoeller KF, Rathod VD. Difficult pancreatic mass FNA: tips for success. Gastrointest Endosc. 2002;56(4 Suppl):S86–91.

    Article  PubMed  Google Scholar 

  • Erickson RA. EUS-guided FNA. Gastrointest Endosc. 2004;60(2):267–79.

    Article  PubMed  Google Scholar 

  • Fisher L, Segarajasingam DS, Stewart C, Deboer WB, Yusoff IF. Endoscopic ultrasound guided fine needle aspiration of solid pancreatic lesions: Performance and outcomes. J Gastroenterol Hepatol. 2009;24(1):90–6.

    Article  PubMed  Google Scholar 

  • Fritscher-Ravens A, Brand B, Bohnacker S, Sriram P, Soehendra N. Technique of endoscopic ultrasonography-guided fine-needle aspiration of the lymph nodes. Tech Gastrointest Endosc. 2000a;2(3):142–8.

    Article  Google Scholar 

  • Fritscher-Ravens A, Broering DC, Sriram PV, Topalidis T, Jaeckle S, Thonke F, et al. EUS-guided fine-needle aspiration cytodiagnosis of hilar cholangiocarcinoma: a case series. Gastrointest Endosc. 2000b;52(4):534–40.

    Article  PubMed  CAS  Google Scholar 

  • Fritscher-ravns A. EUS-Experimental and evolving techniques. Endoscopy. 2006;38(S1):S1–4.

    Google Scholar 

  • Giovannini M. Ultrasound-guided endoscopic surgery. Best Pract Res Clin Gastroenterol. 2004;18:183–200.

    Article  PubMed  CAS  Google Scholar 

  • Kien-Fong Vu C, Chang F, Doig L, Meenan J. A prospective control study of the safety and cellular yield of EUS-guided FNA or Trucut biopsy in patients taking aspirin, nonsteroidal anti-inflammatory drugs, or prophylactic low molecular weight heparin. Gastrointest Endosc. 2006;63(6):808–13.

    Article  PubMed  Google Scholar 

  • Mitsuhashi T, Ghafari S, Chang CY, Gu M. Endoscopic ultrasound-guided fine needle aspiration of the pancreas: cytomorphological evaluation with emphasis on adequacy assessment, diagnostic criteria and contamination from the gastrointestinal tract. Cytopathology. 2006;17(1):34–41.

    Article  PubMed  CAS  Google Scholar 

  • Nguyen YP, Maple JT, Zhang Q, Ylagan LR, Zhai J, Kohlmeier C, et al. Reliability of gross visual assessment of specimen adequacy during EUS-guided FNA of pancreatic masses. Gastrointest Endosc. 2009;69(7):1264–70.

    Article  PubMed  Google Scholar 

  • Noh KW, Woodward TA, Raimondo M, Savoy AD, Pungpapong S, Hardee JD, et al. Changing trends in endosonography: linear imaging and tissue are increasingly the issue. Dig Dis Sci. 2007;52(4):1014–8.

    Article  PubMed  Google Scholar 

  • Puri R, Vilmann P, Săftoiu A, Skov BG, Linnemann D, Hassan H, et al. Randomized controlled trial of endoscopic ultrasound-guided fine-needle sampling with or without suction for better cytological diagnosis. Scand J Gastroenterol. 2009;44(4):499–504.

    Article  PubMed  Google Scholar 

  • Savides TJ. Tricks for improving EUS-FNA accuracy and maximizing cellular yield. Gastrointest Endosc. 2009;69(2 Suppl):S130–3.

    Article  PubMed  Google Scholar 

  • Shah JN, Muthusamy VR. Minimizing complications of endoscopic ultrasound and EUS-guided fine needle aspiration. Gastrointest Endosc Clin N Am. 2007;17(1):129–43. vii-viii.

    Article  PubMed  Google Scholar 

  • Vilmann P, Săftoiu A. Endoscopic ultrasound-guided fine needle aspiration biopsy: equipment and technique. J Gastroenterol Hepatol. 2006;21(11):1646–55.

    Article  PubMed  Google Scholar 

  • Yamao K, Mizuno N, Takagi T, Hara K. How I do it and when I use (and do not use) EUS-FNA. Gastrointest Endosc. 2009;69(2 Suppl):S134–7.

    Article  PubMed  Google Scholar 

  • Yusuf TE, Tsutaki S, Wagh MS, Waxman I, Brugge WR. The EUS hardware store: state of the art technical review of instruments and equipment (with videos). Gastrointest Endosc. 2007;66(1):131–43.

    Article  PubMed  Google Scholar 

  • Yusuf TE, Ho S, Pavey DA, Michael H, Gress FG. Retrospective analysis of the utility of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in pancreatic masses, using a 22-gauge or 25-gauge needle system: a multicenter experience. Endoscopy. 2009;41(5):445–8.

    Article  PubMed  CAS  Google Scholar 

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Acknowledgment

I respectfully acknowledge Dr. Dharma Thiruvaiyaru, Ph.D., Dept. of Mathematics, Statistics and Computer Sciences, Augusta State University, Augusta, Georgia for critically reviewing the chapter.

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Correspondence to Sreeram V. J. Parupudi M.D. .

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Parupudi, S.V.J., Sridhar, S. (2011). Technique of Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA). In: Wu, G., Sridhar, S. (eds) Diagnostic and Therapeutic Procedures in Gastroenterology. Clinical Gastroenterology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59745-044-7_16

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  • DOI: https://doi.org/10.1007/978-1-59745-044-7_16

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