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Imaging

Screening for Spinal Disease
  • A. Jay Khanna
  • Mesfin A. Lemma
  • Bruce A. Wasserman
  • Robert F. McLain
Part of the Current Clinical Oncology book series (CCO)

Abstract

Irrespective of the underlying pathology, treatment for neoplasia of the spine starts only after the disease has been identified and its extent confirmed on an objective study. Whenever there is a suspicion that cancer has involved the spine, an appropriate screening protocol should be initiated to confirm or rule out that suspicion and to provide a differential diagnosis or preliminary diagnosis that will guide initial treatment.

Keywords

Vertebral Compression Fracture Spinal Metastasis Spinal Tumor Spine Magnetic Resonance Imaging Herniate Nucleus Pulposus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Wilson JMG, Junger F. Principles and Practice of Screening for Disease (Public Health Papers No. 34). Geneva, Switzerland: World Health Organization; 1968.Google Scholar
  2. 2.
    Boden SD, McCowin PR, Davis DO, Dina TS, Mark AS, Wiesel S. Abnormal magnetic-resonance scans of the cervical spine in asymptomatic subjects. A prospective investigation. J Bone Joint Surg Am 1990; 72:1178–1184.PubMedGoogle Scholar
  3. 3.
    Jaffe, H.L. Tumors and Tumorous Conditions of the Bones and Joints. Philadelphia, PA: Lea and Febiger; 1958.Google Scholar
  4. 4.
    Weinstein JN, McLain RF. Primary tumors of the spine. Spine 1987; 12:843–851.PubMedCrossRefGoogle Scholar
  5. 5.
    Sim FH, Dahlin DC, Stauffer RN, Laws ER. Primary bone tumors simulating lumbar disc syndrome. Spine 1977; 2:65–74.CrossRefGoogle Scholar
  6. 6.
    Harrington KD. Current concepts review: metastatic disease of the spine. J Bone Joint Surg 1986; 68:1110–1115.PubMedGoogle Scholar
  7. 7.
    McLain RF. Tumors of the spine. In: Chapman’s Orthopaedic Surgery. 3rd ed. Philadelphia, PA: Lippincott, Williams and Wilckins; 2001:3933–3958.Google Scholar
  8. 8.
    Lodwick GS. Determining growth rates of focal lesions of bone from radiographs. Radiology 1980; 134:577–583.PubMedGoogle Scholar
  9. 9.
    Edelstyn GA, Gillespie PJ, Grebell ES. The radiologic demonstration of osseous metastases: experimental observations. Clin Radiol 1967; 18:158–164.PubMedCrossRefGoogle Scholar
  10. 10.
    Wong DA, Fornasier VL, MacNab I. Spinal metastases: the obvious, the occult, and the imposters. Spine 1990; 15:1–4.PubMedCrossRefGoogle Scholar
  11. 11.
    Weinstein JN, McLain RF. Primary tumors of the spine. Spine 1988; 12:843–851.CrossRefGoogle Scholar
  12. 12.
    McLain RF, Weinstein JN. Solitary plasmacytomas of the spine: report of 84 cases. J Spinal Disord 1989; 2:69–74.PubMedCrossRefGoogle Scholar
  13. 13.
    Savelli G, Chiti A, Grasselli G, Maccauro M, Rodari M, Bombardieri E. The role of bone SPET study in diagnosis of single vertebral metastases. Anticancer Res 2000; 20:1115–1120.PubMedGoogle Scholar
  14. 14.
    Gates, GF. SPECT bone scanning of the spine. Semin Nucl Med 1998; 28:78–94.PubMedCrossRefGoogle Scholar
  15. 15.
    Vacarro AR, Shah SH, Schweitzer ME, Rosenfeld JF, Cotler JM. MRI description of vertebral osteomyelitis, neoplasm, and compression fracture. Orthopedics 1999; 22:67–73.Google Scholar
  16. 16.
    Yamaguchi T. Intertrabecular vertebral metastases: metastases only detectable on MR imaging. Semin Musculoskel Radiol 2001; 5:171–175.CrossRefGoogle Scholar
  17. 17.
    Chan JH, Peh WC, Tsui EY, et al. Acute vertebral body compression fractures: Discrimination between benign and malignant causes using apparent diffusion coefficients. Br J Radiol 2002; 75:207–214.PubMedGoogle Scholar
  18. 18.
    Shih TT, Huang KM, Li YW: Solitary vertebral collapse: distinction between benign and malignant causes using MR patterns. J Magn Reson Imaging 1999; 9:635–642.PubMedCrossRefGoogle Scholar
  19. 19.
    McLain RF, Weinstein JN. Tumors of the spine. Seminars in Spine Surgery, 1990; 2:157–180.Google Scholar

Copyright information

© Humana Press, Inc., Totowa, NJ 2006

Authors and Affiliations

  • A. Jay Khanna
    • 1
  • Mesfin A. Lemma
    • 1
  • Bruce A. Wasserman
    • 2
  • Robert F. McLain
    • 3
  1. 1.Johns Hopkins Orthopaedic Surgery at Good Samaritan HospitalBaltimore
  2. 2.Russell H. Morgan Department of Radiology and Radiological ScienceJohns Hopkins Medical InstitutionsBaltimore
  3. 3.Lerner College of Medicine and The Cleveland Clinic Spine Institute, Department of Orthopaedic SurgeryThe Cleveland Clinic FoundationCleveland

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