Genitourinary Oncology

Prostate, Renal, and Bladder Cancer
  • Robert Dreicer
Part of the Current Clinical Oncology book series (CCO)


Among the major genitourinary neoplasms, prostate and renal cell carcinomas rank high among all epithelial neoplasms in the relative incidence of both bone metastases and spinal cord compression (1,2). Although advanced urothelial cancers (primarily bladder cancer) represent a relatively small number of patients, this neoplasm too has a relatively high predilection to spread to bone (3). Although the fundamental management issues of skeletal metastases are similar within these neoplasms, the systemic therapies utilized to treat these diseases are very different; hormonal therapy for prostate cancer, immunotherapy for renal cell cancer, and systemic chemotherapy for advanced urothelial cancers. The relative effectiveness of these diverse therapies impact on some important aspects of the management of metastatic disease to the spine in patients with these neoplasms.


Prostate Cancer Bladder Cancer Bone Metastasis Clin Oncol Spinal Cord Compression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Humana Press, Inc., Totowa, NJ 2006

Authors and Affiliations

  • Robert Dreicer
    • 1
  1. 1.Genitourinary Medical Oncology and Experimental Therapeutics, Department of Hematology/Oncology and the Urologic InstituteThe Cleveland Clinic FoundationCleveland

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