Abstract
No class of drugs has been more popular than the angiotensin-receptor blockers (ARBs). Their side-effect profile has resulted in increasing prescriptions because they are better tolerated than any other class of antihypertensive drugs. The outcome trials (Table 1) with these drugs are now being reported and are showing benefits for target organ protection (1–15). ARBs are proven to be effective in reducing the rate of renal insufficiency among diabetic hypertensives (3,5), reducing strokes for elderly patients (10) and hypertensive patients with left ventricular hypertrophy (7), and reducing cardiovascular mortality and total mortality compared to atenolol in diabetic hypertensive patients (9). Valsartan is as effective as captopril in patients sustaining a myocardial infarction complicated by heart failure, left ventricular dysfunction, or both (15).
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© 2005 Humana Press Inc., Totowa, NJ
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Prisant, L.M. (2005). Use of Angiotensin Receptor Blockers in the Elderly. In: Prisant, L.M. (eds) Hypertension in the Elderly. Clinical Hypertension and Vascular Diseases. Humana Press. https://doi.org/10.1007/978-1-59259-911-0_17
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DOI: https://doi.org/10.1007/978-1-59259-911-0_17
Publisher Name: Humana Press
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