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Plantago ovata

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Abstract

Plantago ovata is a stemless, soft, hairy annual herb of the PLANTAGINACEAE family that grows to a height of 30–45 cm. The leaves are 7.5–23 cm long, 0.5–1 cm broad, narrowly linear, linear lanceolate or filiform, opposite, finely acuminate entire or distantly toothed, attenuated at the base and usually three-nerved. The root system has a well-developed taproot with few fibrous secondary roots. A number of flowering shoots arise from the base of the plant. The flower spikes turn reddish brown at ripening, the lower leaves dry, and the upper leaves yellow. Plants flower approx 60 days after planting. Flowers are numerous, small, and white, in ovoid or cylindrical spikes 1.3–3.8 cm long, bracts 4 mm long and broad. The corolla gives attachment to four protruded stamina, ovary free with one or two cells, containing one or more ovules.

Keywords

  • Bile Acid
  • Dietary Fiber
  • Glycemic Index
  • Arabic Country
  • Fecal Bile Acid

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Siddiqui, H. H., K. K. Kapur, and C. K. Atal. Indian seeds oils. Effect of Plantago ovata embryo oil on serum cholesterol levels in rabbits. Indian J Pharmacy 1964; 26: 266.

    CAS  Google Scholar 

  2. Wattiez, N., and M. Hans. A holoside extracted from the seeds of Plantago major L. and Plantago ovata Forsk (P. isphagulata Roxb.). Bull Acad Roy Med Belg 1943; 8: 386–396.

    CAS  Google Scholar 

  3. Khorana, M. L., V. G. Prabbu, and M. R. R. Rao. Pharmacology of an alcoholic extract of Plantago ovata. Indian J Pharmacy 1958; 29: 3–6.

    Google Scholar 

  4. Gelpi, E., H. Schneider, V. M. Doctor, J. Tennison, and J. Oro. Gas chromatographic-mass spectrometric identifications of the hydrocarbons and fatty acids of Plantago ovata seeds. Phytochemistry 1969; 8(10): 2077–2081.

    CAS  Google Scholar 

  5. Zagari, A. Medicinal plants. Vol. 4, 5th ed, Tehran University Publications, No 1810/4, Tehran, Iran, 1992; 4: 969.

    Google Scholar 

  6. Sander, E. H. Psylium-hydrocolloid gum compositions and fiber supplements. Paten-Can Pat Appl-2,100,295 1994; 17 p.

    Google Scholar 

  7. Gelissen, C., B. Brodie, and M. A. Eastwood. Effect of Plantago ovata (psyllium) husk and seeds on sterol metabolism: studies in normal and ileostomy subjects, Amer J Clin Nutr 1994; 59(2): 395–400.

    PubMed  CAS  Google Scholar 

  8. Nordgaard, I., H. Hove, M. R. Clausen, and P. B. Mortensen. Colonic production of butyrate in patients with previous colonic cancer during long-term treatment with dietary fiber (Plantago ovata seeds). Scand J Gastroenterol 1996; 31(10): 1011–1020.

    PubMed  CAS  Google Scholar 

  9. Kritschevsky, D., S. A. Tepper, and D. M. Klurfeld. Influence of psyllium preparations on plasma and liver lipids of cholesterol-fed plants. Artery 1995; 21(6): 303–311.

    Google Scholar 

  10. Davidson, M. H., L. D. Dugan, J. H. Burns, D. Sugimoto, K. Story, and K. Drennan. A psyllium-enriched cereal for treatment of hypercholesterolemia in children: a controlled, double blind, crossover study. Amer J Clin Nutr 1996; 63(1): 96–102.

    PubMed  CAS  Google Scholar 

  11. Olson, B. H., S. M. Anderson, M. P. Becker, et al. Psyllium-enriched cereals lower blood total cholesterol and LDL cholesterol, but not HDL cholesterol, in hypercholesterolemic adults: results of a meta-analysis. J Nutr 1997; 127(10): 1973–1980.

    PubMed  CAS  Google Scholar 

  12. Odes, H. S., and Z. Madar. A double-blind trial of a celandine, Aloe vera and psyllium laxative preparation in adult patients with constipation. Digestion 1991; 49(2): 65–71.

    PubMed  CAS  Google Scholar 

  13. Cohen, L. A., Z. Zhao, E. A. Zhang, T. T. Wynn, B. Simi, and A. Rivenson. Wheat bran and psyllium diets: effects on N-methylnitrosourea-induced mammary tumorigenesis in F344 rats. J Nat Cancer Inst 1996; 88(13): 898–907.

    Google Scholar 

  14. Davidson, M. H., K. C. Maki, J. C. Kong, et al. Long-term effects of consuming food containing psyllium seed husk on serum lipids in subjects with hypercholesterolemia. Amer J Clin Nutr 1998; 67(3): 367–376.

    PubMed  CAS  Google Scholar 

  15. Segawa, K., T. Kataoka, and Y. Fukuo. Cholesterol-lowering effects of psyllium seed associated with urea metabolism. Biol Pharm Bull 1998; 21(2): 184–187.

    PubMed  CAS  Google Scholar 

  16. Riguad, D., F. Paycha, A. Muelemans, M. Merrouche, and M. Mignon. Effect of psyllium on gastric emptying, hunger feeling, and food intake in normal volunteers: a double-blind study. European J Clin Nutr 1998; 52(4): 239–245.

    Google Scholar 

  17. Arlian, L. G., D. L. Vyszenski-Noher, A. T. Lawrence, K. R. Schrotel, and H. L. Ritz. Antigenic and allergenic analysis of psyllium seed components. J Allergy Clin Immunol 1992; 89(4): 866–876.

    PubMed  CAS  Google Scholar 

  18. Anderson J. W., S. Riddell-Mason, N. J. Gustafson, S. F. Smith, and M. Mackey. Cholesterol-lowering effects of psyllium-enriched cereal as an adjunct to a prudent diet in the treatment of mild to moderate hypercholesterolemia. Amer J Clin Nutr 1992; 56(1): 93–98.

    PubMed  CAS  Google Scholar 

  19. Day, C. E. Activity of psyllium hydrophilic colloid for reducing serum cholesterol in sea quail fed diet supplemented with cholesterol. Artery 1991; 18(3): 163–167.

    PubMed  CAS  Google Scholar 

  20. McCall, M. R., T. Mehta, C. W. Leathers, and D. M. Foster. Psyllium husk II. Effect on the metabolism of apoliprotein B in African green monkeys. Amer J Clin Nutr 1992; 56(2): 385–393.

    PubMed  CAS  Google Scholar 

  21. James, J. M., S. K. Cooke, A. Barnett, and H. A. Sampson. Anaphylactic reactions to a psyllium-containing cereal. J Allergy Clin Immunol 1991; 88(3): 402–408.

    PubMed  CAS  Google Scholar 

  22. Everson, G. T., B. P. Daggy, C. Mc Kinley, and J. A. Story. Effect of psyllium hydrophilic mucilloid on LDL-cholesterol and bile acid synthesis in hypercholesterolemic men. J Lipid Res 1992; 33(8): 1183–1192.

    PubMed  CAS  Google Scholar 

  23. Tomlin, J., and N. W. Read. A comparative study of the effects on colon function caused by feeding ispaghula husk and polydextrose. Aliment Pharmacol Ther 1988; 2(6): 513–519.

    PubMed  CAS  Google Scholar 

  24. Bergmann, J. F., O. Chassany, A. Petit, R. Triki, C. Caulin, and J. M. Segrestaa. Correlation between echographic gastric emptying and appetite: Influence of psyllium. Gut 1992; 33(8): 1042–1043.

    PubMed  CAS  Google Scholar 

  25. McCall, M. R., T. Mehta, C. W. Leathers, and D. M. Foster. Psyllium husk I. Effect on plasma lipoprotein, cholesterol metabolism, and artherosclerosis in African green monkeys. Amer J Clin Nutr 1992; 56(2): 376–384.

    PubMed  CAS  Google Scholar 

  26. Smith, M. A., and A. A. Aso. Comparison of psyllium hydrophilic mucilloid and bile salt binding resin therapy for hypercholesterolemia. Abstr Endocrine Society 144th Annual Meeting June 1992; 62.

    Google Scholar 

  27. Hopewell, R., R. Yeater, and I. Ullrich. Soluble fiber: Effect on carbohydrate and lipid metabolism. Progress Food Nutr Sci 1993; 17(2): 159–182.

    CAS  Google Scholar 

  28. Eherer, A. J., A. Santa, A. Carol, J. Porter, and J. S. Fordtran. Effect of psyllium, calcium polycarbophil, and wheat bran on secretory diarrhea induced by phenolphthalein. Gastroenterology 1993; 104(4): 1007–1012.

    PubMed  CAS  Google Scholar 

  29. Colliopoulos, J. Psyllium-based laxative compositions. Patent-US-5,232, 699 1993; 6 p.

    Google Scholar 

  30. Gupta, S., J. N. S. Yadava, and J. S. Tandon. Antisecretory (antidiarrheal) activity of Indian medicinal plants against Escherichia coli enterotoxin-induced secretion in rabbit and Guinea pig ileal loop models. Int J Pharmacog 1993; 31(3): 198–204.

    Google Scholar 

  31. Passmore, A. P., K. Wilson-Davies, C. Stoker, and M. E. Scott. Chronic constipation in long stay elderly patients: a comparison of lactulose and a senna-fiber combination. Brit Med J 1993; 307(6907): 769–771.

    PubMed  CAS  Google Scholar 

  32. Wolever, T., D. Jenkins, S. Mueller, et al. Method of administration influences the serum cholesterol lowering effect of psyllium. Amer J Clin Nutr 1994; 59(5): 1055–1059.

    PubMed  CAS  Google Scholar 

  33. Turley, S.D., B. P. Daggy, and J. M. Dietschy. Psyllium augments the cholesterol-lowering action of cholestyramine in hamsters by enhancing sterol loss from the liver. Gastroenterology 1994; 107(2): 444–452.

    PubMed  CAS  Google Scholar 

  34. Naylor, J. M. and T. Lieber. Effect of psyllium on plasma concentration of glucose, breath hydrogen concentration, and fecal composition in calves with diarrhea treated orally with electrolyte solutions. Amer J Vet Res 1995; 56(1): 56–59.

    PubMed  CAS  Google Scholar 

  35. Ganji, V. and C. V. Kies. Psyllium husk fiber supplementation to soybean and coconut oil diets of humans: effect on rat digestibility and fecal fatty acid excretion. Eur J Clin Nutr 1994; 48(8): 595–597.

    PubMed  CAS  Google Scholar 

  36. Matheson, H. B. and J. A. Story. Dietary psylium hydrocolloid and pectin increase bile acid pool size and change bile acid composition in rats. J Nutr 1994; 124(8): 1161–1165.

    PubMed  CAS  Google Scholar 

  37. Freeman, G. L. Psyllium hypersensitivity. Ann Allergy 1994; 73(6): 490–492.

    PubMed  CAS  Google Scholar 

  38. Turley, S. D., and J. M. Dietschy. Mechanisms of LDL-cholesterol lowering action of psyllium hydrophilic mucilloid in the hamster. Biochim Biophys Acta 1995; 1255(2): 177–184.

    PubMed  Google Scholar 

  39. Gupta, B. R., C. G. Agrawal, G. P. Singh, and A. Ghatak. Lipid-lowering efficacy of psyllium hydrophilic mucilloid in non insulin dependent diabetes mellitus with hyperlipidaemia. Indian J Med Res 1994; 100(5): 237–241.

    PubMed  CAS  Google Scholar 

  40. Chan, E. K., and D J. Schroeder. Psyllium in hypercholesterolemia. Ann Pharmacother 1995; 29(6): 625–627.

    PubMed  CAS  Google Scholar 

  41. Ewe, K., B. Uberschaer, and A. G. Press. Influence of senna, fiber, and fiber+senna on colonic transit in lopermaide-induced constipation. Pharmacology 1993; 47(1): 242–248.

    PubMed  CAS  Google Scholar 

  42. Williams, C. L., M. Bollella, A. Spark, and D. Puder. Soluble fiber enhances the hypercholesterolemic effect of the step I diet in childhood. J Amer Coll Nutr 1995; 14(3): 251–257.

    CAS  Google Scholar 

  43. Turnbull, W. H., and H. G. Thomas. The effect of a Plantago ovata seed containing preparation of appetite variables, nutrient, and energy intake. Int J Obesity 1995; 19(5): 338–342.

    CAS  Google Scholar 

  44. Etman, M. A. Effect of a bulk forming laxative on the bioavailability of carbamazepine in man. Drug Dev Ind Pharm 1995; 21(16): 1901–190.

    CAS  Google Scholar 

  45. Martinez-Lirola, M. J., M. R. Gonzalez-Tejero, and J. Molero-Mesa. Ethnobotanical resources in the province of Almeria, Spain: Campos de Nijar. Econ Bot 1996; 50(1): 40–56.

    Google Scholar 

  46. Arjmandi, B. H., E. Sohn, S. Juma, S. R. Murthy, and B. P. Daggy. Native and partially hydrolyzed psyllium has comparable effects on cholesterol metabolism in rats. J Nutr 1997; 127(3): 463–469.

    PubMed  CAS  Google Scholar 

  47. Jenkins, D., T. Wolever, E. Vidgen, et al. Effect of psyllium in hypercholesterolemia at two monounsaturated fatty acid intakes. Amer J Clin Nutr 1997; 65(5): 1524–1533.

    PubMed  CAS  Google Scholar 

  48. Prior, A., and P. J. Whorwell. Double blind study of Ispaghula in irritable bowel syndrome. Gut 1987; 28: 1510–1513.

    PubMed  CAS  Google Scholar 

  49. Jamal, S., I. Ahmad, R. Agarwal, M. Ahamad, and S. M. Osman. A novel oxo fatty acid in Plantago ovata seed oil. Phytochemistry 1987; 26(11): 3067–3069.

    CAS  Google Scholar 

  50. Miettinen, T. A., and S. Tarpila. Serum lipids and cholesterol metabolism during guar gum, Plantago ovata and high fiber treatments. Clinica Chim Acta 1989; 183: 253–262.

    CAS  Google Scholar 

  51. Watters, K., and P. Blaisdell. Reduction of glycemic and lipid levels in DB/DB diabetic mice by psyllium plant fiber. Diabetes 1989; 38(12): 1528–1533.

    PubMed  CAS  Google Scholar 

  52. Shah, G. L. and G. V. Gopal. Ethno-medical notes from the tribal inhabitants of the north Gujarat (India). J Econ Taxon Botany 1985; 6(1): 193–201.

    Google Scholar 

  53. Enzi, G., E. M. Inelmen, and G. Crepaldi. Effect of a hydrophilic mucilage in the treatment of obese patients. Pharmacotherapeutica 1980; 2(7): 421–428.

    CAS  Google Scholar 

  54. Lantner, R. R., B. R. Espiritu, P. Zumerchik, and M. C. Tobin. Anaphylaxis following ingestion of a psyllium-containing cereal. JAMA 1990; 264(19): 2534–2536.

    PubMed  CAS  Google Scholar 

  55. Pastors, J. G., P. W. Blaisdell, T. K. Balm, C. M. Asplin, and S. L. Pohl. Psyllium fiber reduces rise in postprandial glucose and insulin concentrations in patients with non-insulin-dependent diabetes. Amer J Clin Nutr 1991; 53(6): 1431–1435.

    PubMed  CAS  Google Scholar 

  56. Wolever, T. M. S., V. Vuksan, H. Eshuis, et al. Effect of method of administration of psyllium on glycemic response and carbohydrate digestibility. J Amer Coll Nutr 1991; 10(4): 364–371.

    CAS  Google Scholar 

  57. Naovi, S. A. H., M. S. Y. Khan, and S. B. Vohora. Anti-bacterial, anti-fungal and anthelmintic investigations on Indian medicinal plants. Fitoterapia 1991; 62(3): 221–228.

    Google Scholar 

  58. Ricci, P. D., and R. Angeli. Plantago ovata and defecation disorders in the aged. Effects of the administration of powdered Plantago ovata on defecation disorders in the aged. Clin Ter 1978; 86: 434–439.

    PubMed  CAS  Google Scholar 

  59. Khanna, N. M., J. P. S. Sarin, R. C. Nandi, et al. Isaptent—a new cervical dilator. Contraception 1980; 21: 29–40.

    PubMed  CAS  Google Scholar 

  60. Sandhu, J. S., G. J. Hudson, and J. F. Kennedy. The gel nature and structure of the carbohydrate of Ispaghula husk. Carbohydr Res 1981; 93: 247–259.

    CAS  Google Scholar 

  61. Jewvachdamrongkul, Y., T. Dechatiwongtse, D. Pecharaply, J. Bansiddhi, and P. Kanchanapee. Identification of some Thai medicinal plants. Mahidol Univ J Pharm Sci 1982; 9(3): 65–73.

    CAS  Google Scholar 

  62. Patel, R. B., C. G. Rana, M. R. Patel, H. K. Dhyani, and H. V. Chauhan. Chromatographic screening of proteins of seeds of Plantago ovata Forsk. Indian Drugs Pharm Ind 1981; 16: 3–5.

    CAS  Google Scholar 

  63. Roy, P. Mid trimester abortion by slow dilatation with Isapgol tents (Dilexc). Patna J Med 1982; 56(5): 95–97.

    Google Scholar 

  64. Vijayalakshimi, K., S. D. Mishra, and S. K. Prasad. Nematocidal properties of some indigenous plant materials against second stage juveniles of Meloidogyne incognita (koffoid and white) chitwood. Indian J Entomol 1979; 41(4): 326–331.

    Google Scholar 

  65. Al-Shamma, A., and L. A. Mitscher. Comprehensive survey of indigenous Iraqi plants for potential economic value. I. Screening results of 327 species for alkaloids and antimicrobial agents. J Nat Prod 1979; 42: 633–642.

    PubMed  CAS  Google Scholar 

  66. Shukla, P. C., M. C. Desai, L. P. Purohit, and H. B. Desai. Use of Isabgul (Plantago ovata Forsk.) gola in the concentrate mixture of milk cows. Gujarat Agr Univ Res 1983; 9(1): 33–36.

    Google Scholar 

  67. Toth, B. Effect of Metamucil on tumor formation by 1,2-dimethylhydrazine dihydrochloride in mice. Food Chem Toxicol 1984; 22(7): 573–578.

    PubMed  CAS  Google Scholar 

  68. Dooley, D. P., M. Rhodes, and D. Drehner. Psyllium worm. Amer J Gastroenterol 1993; 88(1): 153–154.

    CAS  Google Scholar 

  69. Alabaster, O., Z. C. Tang, A. Frost, and N. Shivapurkar. Potential synergism between wheat bran and psyllium: enhanced inhibition of colon cancer. Cancer Lett 1993; 75(1): 53–58.

    PubMed  CAS  Google Scholar 

  70. Atal, C. K., K. K. Kapoor, and H. H. Siddiqui. Studies on Indian seed oils. Part I. Preliminary screening of linoleic acid rich oils. Indian J Pharmacy 1964; 26; 163–164.

    CAS  Google Scholar 

  71. Siddiqui, H. H., K. K. Kapoor, and C. K. Atal. Studies on Indian seed oils. Part II. Effect of Plantago ovata embryo oil on raised serum cholesterol levels in rabbits. Indian J Pharmacy 1964; 26: 1663–1664.

    Google Scholar 

  72. Wasicky, B. Investigations of the seeds of Plantago ovata, P. psyllium, and P. major variety cruenta as laxatives. Planta Med 1961; 9: 232–244.

    CAS  Google Scholar 

  73. Balbaa, S. I., M. S. Karawaya, and M. S. Afifi. Pharmacognostical study of the seeds of certain Plantago species growing in Egypt. UAR J Pharm Sci 1971; 12(1): 35–52.

    CAS  Google Scholar 

  74. Salguero Molpeceres O., M. C. Seijas Ruiz-Coello, J. Hernandez-Nunez, D. Caballos Villar, L. Diaz Picazo, and L. Ayerbe Garcia-Monzon. Esophageal obstruction caused by dietary fiber from Plantago ovata, a complication preventable by adequate information. Gastroenterologia y Hepatologia 2003; 26(4): 248–250.

    PubMed  CAS  Google Scholar 

  75. Rodriguez-Cabezaz, M. E., J. Galvez, M. D. Lorente, et al. Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid—induced colitis rats. J Nutr 2002; 132(11): 3263–3271.

    Google Scholar 

  76. Romero, A. L., K. L. West, T. Zern, and M. L. Fernandez. The seeds from Plantago ovata lower plasma lipids by altering hepatic ad bile acid metabolism in guinea pigs. J Nutr 2002; 132(6): 1194–1198.

    PubMed  CAS  Google Scholar 

  77. Chiang, L. C., W. Chiang, M. Y. Chiang, L. T. Ng, and C. C. Lin. Anti-leukemic activity of selected natural products in Taiwan. Amer J Chin Med 2003; 31(1): 37–46.

    CAS  Google Scholar 

  78. Rezaeipoor, R., S. Saednia, and M. Kamalinejad. The effect of Plantago ovata on humoral immune responses in experimental animals. J Ethnopharmacol 2000; 72(1–2): 283–286.

    PubMed  CAS  Google Scholar 

  79. Rodriguez-Moran, M., F. Guerrero-Romero, and G. Lazcano-Burciaga. Lipid-and glucose-lowering efficacy of Plantago psyllium in type II diabetes. J Diabet Complic 1998; 12(5): 273–278.

    CAS  Google Scholar 

  80. Frati-Munari, A. C., W. Benitez Pinto, C. Raul Ariza Andraca, and M. Casarrubias. Lowering glycemic index of food by acarbose and Plantago psyllium mucilage. Arch Med Res 1998; 29(2): 137–141.

    PubMed  CAS  Google Scholar 

  81. Moran, S., M. Uribe, M. E. Prado, et al. Effects of fiber administration in the prevention of gallstones in obese patients on a reducing diet. A clinical trial. Revista de Gastroenterologia de Mexico 1997; 62(4): 266–272.

    PubMed  CAS  Google Scholar 

  82. Perez-Miranda, M., A. Gomez-Cedenilla, T. Leon-Colombo, J. Pajares, and J. Mate-Jimenez. Effect of fiber supplements on internal bleeding hemorrhoids. Hepato-Gastroener 1996; 43(12): 1504–1507.

    CAS  Google Scholar 

  83. Nordgaard, I., H. Howe, M. R. Clausen, and P. B. Mortensen. Colonic production of butyrate in patients with previous colonic cancer during long-term treatment with dietary fiber. Scand J Gastroenter 1996; 31(10): 1011–1020.

    CAS  Google Scholar 

  84. Frati-Munai, A. C., M. A. Flores-Garduno, R. Ariza-Andraca, S. Islas-Andrade, and A. Chavez-Negrete. Effect of different doses of Plantago psyllium mucilage on the glucose tolerance test. Archivos de Investigacion Medica 1989; 20(2): 147–152.

    Google Scholar 

  85. Westerhof, W., P. K. Das, E. Middlelkoop, J. Verschoor, L. Storey, and C. Regnier. Mucopolysaccharides from psyllium involved in wound healing. Drugs Under Exp Clin Res 2001; 27(5–6): 165–175.

    CAS  Google Scholar 

  86. Aleman, A. M., S. Quirce, C. Bombin, and J. Sastre. Asthma related to inhalation of Plantago ovata. Med Clin 2001; 116(1): 20–22.

    CAS  Google Scholar 

  87. Fernandez-Banares, F., J. Hinojosa, J. L. Sanchez-Lombrana, et al. Randomized clinical trial of Plantago ovata seeds (dietary fiber) as compared with mesalamine in maintaining remission in ulcerative colitis. Spanish Group for the Study of Crohn’s Disease and Ulcerative Colitis (GETECCU). Amer J Gastroenterol 1999; 94(2): 427–433.

    CAS  Google Scholar 

  88. Fernanzed, N., M. J. Diez, M. T. Teran, J. J. Garcia, A. P. Calle, and M. Sierra. Influence of two commercial fibers in the pharmacokinetics of ethinyl-estradiol in rabbits. J Pharmacol Exp Therap 1998; 286; 870–874.

    Google Scholar 

  89. Voderholzer, W.A., W. Schatke, B. E. Muhldorfer, A. G. Klauser, B. Birkner, and S. A. Muller-Lissner. Clinical response to dietary fiber treatment of chronic constipation. Amer J Gastroenterol 1997; 92(1): 95–98.

    CAS  Google Scholar 

  90. Gelissen, I. C., and M. A. Eastwood. Taurocholic acid adsorption during non-starch polysaccharide fermentation: an in vitro study. Brit J Nutr 1995; 74(2): 221–228.

    PubMed  CAS  Google Scholar 

  91. Turnbull, W. H., and H. G. Thomas. The effect of a Plantago ovata seed containing preparation on appetite variables, nutrient and energy intake. Int J Obesity Rel Metab Disord 1995; 19(5): 338–342.

    CAS  Google Scholar 

  92. Marteau, P., B. Flourie, C. Cherbut, et al. Digestibility and bulking effect of ispaghula husk in healthy humans. Gut 1994; 35(12): 1747–1752.

    PubMed  CAS  Google Scholar 

  93. Freeman, G. L. Psyllium hypersensitivity. Ann Allergy 1994; 73(6): 490–492.

    PubMed  CAS  Google Scholar 

  94. Gelissen, I. C., B. Brodie, and M. A. Eastwood. Effect of Plantago ovata (psyllium) husk and seeds on sterol metabolism: studies in normal and ileostomy subjects. Amer J Clin Nutr 1994; 59(2): 395–400.

    PubMed  CAS  Google Scholar 

  95. Edwards, C. A., J. Bowen, W. G. Brydon, and M. A. Eastwood. The effect of ispaghula on rat caecal fermentation and stool output. Brit J Nutr 1992; 68(2): 473–482.

    PubMed  CAS  Google Scholar 

  96. Tomas-Ridicci, M., R. Anon, M. Minguez, A. Zaragoza, J. Ballester, and A. Benages. The efficacy of Plantago ovata as a regulator of intestinal transit. A double-blind study compared to placebo. Revista Espanola de Enfermedades Digestivas 1992; 82(1): 17–22.

    Google Scholar 

  97. Leng-Peschlow, E. Plantago ovata seeds as dietary fiber supplement: physiological and metabolic effects in rats. Br J Nutr 1991; 66(2): 331–349.

    PubMed  CAS  Google Scholar 

  98. Leng-Peschlow, E. Interference of dietary fibers with gastrointestinal enzymes in vitro. Digestion 1989; 44(4): 200–210.

    PubMed  CAS  Google Scholar 

  99. Miettinen, T. A. and S. Tarpila. Serum lipids and cholesterol metabolism during guar gum, Plantago ovata and high fiber treatments. Clin Chim Acta 1989; 183; 253–262.

    PubMed  CAS  Google Scholar 

  100. Faber, P., and A. Strenge-Hesse. Relevance of rhein excretion into breast milk. Pharmacology 1988; 1(Suppl 36): 212–220.

    Google Scholar 

  101. Suhonen, R., I. Kantola, and F. Bjorksten. Anaphylactic shock due to ingestion of psyllium laxative. Allergy 1983; 38(5): 363–365.

    PubMed  CAS  Google Scholar 

  102. Harborne, J. B., and C. A. Williams. Comparative biochemistry of flavonoids. XIII. 6-Hydroxyluteolin and scutellarein as phyletic markers in higher plants. Phytochemistry 1971; 10: 367–378.

    CAS  Google Scholar 

  103. Machado, L., O. Zetterstrom, and E. Fagerberg. Occupational allergy in nurses to a bulk laxative. Allergy 1979; 34(1): 51–55.

    PubMed  CAS  Google Scholar 

  104. Lerman Garber, I., M. Lagunas, J. C. Sierra Perez, et al. The effect of psyllium plantago in slightly to moderately hypercholesterolemic patients. Archives del Instituto de Cardiologia de Mexico 1990; 606): 535–539.

    Google Scholar 

  105. Uribe, M., M. Dibildox, S. Malpica, et al. Beneficial effect of vegetable protein diet supplemented with psyllium plantago in patients with hepatic encephalopathy and diabetes mellitus. Gastroenterology 1985; 88(4): 901–907.

    PubMed  CAS  Google Scholar 

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(2005). Plantago ovata. In: Medicinal Plants of the World, Volume 3. Humana Press. https://doi.org/10.1007/978-1-59259-887-8_12

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  • DOI: https://doi.org/10.1007/978-1-59259-887-8_12

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-129-5

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