Abstract
Some primitive autonomic ganglia transform into neurons, some into satellite and neurolemma cells associated with neurons, and others become distinct endocrine elements. The latter stain brown with chrome salts and are thus designated chromaffin cells. This reaction is due to the presence of the hormone epinephrine contained within the cells. The chromaffin system consists of various aggregates of these cells throughout the body. The adrenal medulla is the most prominent member of the group.
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Burgoyne RD, Morgan A, Robinson I, Pender N, Cheek TR. Exocytosis in adrenal chromaffin cells. J Anat 1993;183:309.
Evans DB, Lee JE, Merrell RC, Hickey RC. Adrenal medullary disease in multiple endocrine neoplasia type 2. Appropriate management. Endocrinol Metab Clin North Amer 1994;23:167.
Graham PE, Smythe GA, Lazarus L. Laboratory diagnosis of pheochromocytoma: which analytes should we measure? Ann Clin Biochem 1993;30:129.
Ilias I, Yu J, Carrasquillo JA, Chen CC, Eisenhofer G, Whatley M, McElroy B, Pacak K. Superiority of 6-[18F]-fluorodopamine positron emission tomography versus [131I]-metaiodobenzyl-guanidine scintigraphy in the localization of metastatic pheochromocytoma. J Clin Endocrinol Metab 2003;88:4083.
Kobayashi H, Yanagita T, Yokoo H, Wada A. Pathophysiological function of adrenomedullin and proadrenomedullin N-terminal peptides in adrenal chromaffin cells. Hypertens Res 2003;(Suppl):S71.
Lenders JWM, Pacak K, Walther MM, Linehan WM, Mannelli M, Friberg P, Keiser HR, Goldstein DS, Eisenhofer G. Biochemical diagnosis of pheochromocytoma: which test is best? JAMA 2002;287:1427.
Nagatsu T. Genes for human catecholamine-synthesizing enzymes. Neurosci Res 1991;12:315.
Nativ O, Grant CS, Sheps SG, O’Fallon JR, Farrow GM, van Heerden JA, Lieber MM. The clinical significance of nuclear DNA ploidy pattern in 184 patients with pheochromocytoma. Cancer 1992;69:2683.
Raum WJ. Pheochromocytoma. In: Bardin CW, ed. Current Therapy in Endocrinology and Metabolism, 5th Ed. St. Louis, MO: Mosby 1994:172.
Whitworth EJ, Kosti O, Renshaw D, Hinson JP. Adrenal neuropeptides: regulation and interaction with ACTH and other adrenal regulators. Microsc Res Tech 2003;61:259.
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© 2005 Humana Press Inc., Totowa, NJ
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Raum, W.J. (2005). Adrenal Medulla (Catecholamines and Peptides). In: Melmed, S., Conn, P.M. (eds) Endocrinology. Humana Press. https://doi.org/10.1007/978-1-59259-829-8_22
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DOI: https://doi.org/10.1007/978-1-59259-829-8_22
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