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Nucleic Acid Therapeutics

An Introduction

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Book cover Nucleic Acid Therapeutics in Cancer

Part of the book series: Cancer Drug Discovery and Development ((CDD&D))

Abstract

The development of simple, reliable tools for modifying gene expression “on demand” would represent a major technical advance for cell biologists. Because much progress has been made in understanding the molecular pathogenesis of many diseases, we may easily hypothesize that these same tools could be of tremendous importance to clinicians as well. For example, many genes responsible for cellular transformation have been identified. If the function of these genes were shown to be either completely or relatively tumor specific, they would become legitimate targets for therapeutic manipulation of their expression. More effective, less toxic cancer treatments could reasonably be expected to result if the strategy were successful.

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Authors
  1. Alan M. Gewirtz MD
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Editors and Affiliations

  1. Department of Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA

    Alan M. Gewirtz MD

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Gewirtz, A.M. (2004). Nucleic Acid Therapeutics. In: Gewirtz, A.M. (eds) Nucleic Acid Therapeutics in Cancer. Cancer Drug Discovery and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-777-2_2

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  • DOI: https://doi.org/10.1007/978-1-59259-777-2_2

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9858-5

  • Online ISBN: 978-1-59259-777-2

  • eBook Packages: Springer Book Archive

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