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IGF-Independent Actions of the IGF Binding Proteins

  • Chapter
The IGF System

Part of the book series: Contemporary Endocrinology ((COE,volume 17))

Abstract

The insulin-like growth factor binding proteins (IGFBPs) are members of the IGF signaling system, along with the ligands (insulin, IGF-I, and IGF-II) and a family of transmembrane receptors (the insulin, type 1 IGF and type 2 IGF receptors) (1–11). The human IGFBP superfamily consists of six high-affinity IGF binders (IGFBPs 1–6) and four low-affinity IGF binders (IGFBP-related proteins [IGFBP-rPs] 1–4) (12–15) (Table 1; see Chapter 14 for more detail).

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Authors
  1. Youngman Oh PhD
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  2. Ron G. Rosenfeld MD
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Editors and Affiliations

  1. Department of Pediatrics, School of Medicine, Oregon Health Sciences University, Portland, OR, USA

    Ron G. Rosenfeld MD

  2. Oregon Health Sciences University, Portland, OR, USA

    Charles T. Roberts Jr. PhD

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Oh, Y., Rosenfeld, R.G. (1999). IGF-Independent Actions of the IGF Binding Proteins. In: Rosenfeld, R.G., Roberts, C.T. (eds) The IGF System. Contemporary Endocrinology, vol 17. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-712-3_11

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  • DOI: https://doi.org/10.1007/978-1-59259-712-3_11

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