Abstract
Under ordinary conditions, the principal catecholamine that regulates cardiac function is the norepinephrine (NE) liberated from the sympathetic nerve endings in the heart. In this chapter, initially, the factors that regulate the release of NE and its concentration in the cardiac interstitium are discussed. The various factors that govern the rate at which the cardiac responses develop in response to the initiation of sympathetic neural activity, and that govern the rate at which those responses decay when that activity ceases, are then considered. Because the neural control of the heart depends on the antagonistic influence of the two divisions of the autonomic nervous system (ANS), the powerful influence of the sympathetic and parasympathetic interactions on cardiac performance are then described in detail.
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Levy, M.N. (1999). Catecholamines and the Heart. In: Share, L. (eds) Hormones and the Heart in Health and Disease. Contemporary Endocrinology, vol 21. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-708-6_6
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DOI: https://doi.org/10.1007/978-1-59259-708-6_6
Publisher Name: Humana Press, Totowa, NJ
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