Abstract
When we think of the state of bioethics at the present time, the moral dimensions of stem cell research and cloning, genetic therapy and counseling, reproductive interventions, organ and tissue transplantation, and life-prolonging (sometimes better described as dying-prolonging) technologies come to mind. All of these issues have come to the forefront because of the incredible and almost unimaginable advances in biology, chemistry, physics, and electronics over the past quarter of a century, which have greatly increased the potential for enhancing human wellbeing. Our cultural values and laws have barely been able to deal, in a coherent way, with the opportunities and dangers posed by the advances which are resulting from this accelerated pace of scientific development. The media, and people at large, are often supportive of these technologies because, although the creation and destruction of new human life and the transformation of human embryos into stem cells are often the “collateral damage” of this research, the focus is generally on how well off everyone would be if we could just develop the research into new and better therapeutic applications. Scientists working in these fields are almost always asking for government support without any restrictive legal guidelines or prohibitions. I believe that it is up to bioethicists to ask the difficult (and often unpopular) ethical questions that relate to contemporary advances in biomedical research that will guide both scientists and public policy in the years to come.
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Notes and References
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This is the text of the document as it appeared in the FEDERAL REGISTER on November 2. 2001: DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health, National Institutes of Health Guidelines for Research Using Human Pluripotent Stem Cells ACTION: Notice; withdrawal of NIH Guidelines for Research Using Pluripotent Stem Cells Derived from Human Embryos (published August 25, 2000, 65 FR 51976, corrected November 21, 2000, 65 FR 69951). SUMMARY: The National Institutes of Health (NIH) announces the withdrawal of those sections of the NIH Guidelines for Research Using Human Pluripotent Stem Cells, http://www.nih.gov/news/stemcell/stemcellguidelines.htm. (NIH Guidelines), that pertain to research involving human pluripotent stem cells derived from human embryos that are the result of in vitro fertilization, are in excess of clinical need, and have not reached the stage at which the mesoderm is formed. The President has determined the criteria that allow federal funding for research using existing embryonic stem cell lines, http://www.whitehouse.gov/news/releases/2001/08/print/200108091.html. Thus, the NIH Guidelines as they relate to human pluripotent stem cells derived from human embryos are no longer needed.FOR FURTHER INFORMATION CONTACT: NIH Office of Extramural Research, NIH, 1 Center Drive, MSC 0152, Building Recent Ethical Controversies About Stem Cell Research 119 1, Room 146, Bethesda, MD 20892, or e-mail DDER@nih.gov.
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“As a result of private research, more than 60 genetically diverse stem cell lines already exist.” I have concluded that we should allow federal funds to be used for research on these existing stem cell lines “where the life and death decision has already been made.” This allows us to explore the promise and potential of stem cell research “without crossing a fundamental moral line by providing taxpayer funding that would sanction or encourage further destruction of human embryos that have at least the potential for life.” —George W. Bush
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McCartney, J.J. (2004). Recent Ethical Controversies About Stem Cell Research. In: Humber, J.M., Almeder, R.F. (eds) Stem Cell Research. Biomedical Ethics Reviews. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-674-4_5
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