Endocrinology pp 377-391 | Cite as

Adrenal Medulla (Catecholamine and Peptides)

  • William J. Raum


Some primitive autonomic ganglia transform into neurons, some into satellite and neurolemma cells associated with neurons, and others become distinct endocrine elements. The latter stain brown with chrome salts and are thus designated chromaffin cells. This reaction is the result of the presence of the hormone, epinephrine, contained within the cells. The chromaffin system consists of various aggregates of these cells throughout the body. The adrenal medulla is the most prominent member of the group.


Tyrosine Hydroxylase Vasoactive Intestinal Peptide Chromaffin Cell Adrenal Medulla Catecholamine Secretion 
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Selected Readings

  1. Burgoyne R D, Morgan A, Robinson I, Pender N, Cheek T R. Exocytosis in adrenal chromaffin cells. J Anat 1993; 183: 309.PubMedGoogle Scholar
  2. Evans D B, Lee J E, Merrell R C, Hickey R C. Adrenal medullary disease in multiple endocrine neoplasia type 2. Appropriate management. Endocrin Metab Clin North Am 1994; 23: 167.Google Scholar
  3. Graham P E, Smythe G A, Lazarus L. Laboratory diagnosis of pheochromocytoma: which analytes should we measure? Ann Clin Biochem 1993; 30: 129.PubMedGoogle Scholar
  4. Hinson J P, Cameron L A, Purbrick A, Kapas S. The role of neuropeptides in the regulation of adrenal vascular tone: effects of vasoactive intestinal polypeptide, substance P, neuropeptide Y, neurotensin, Met-enkephalin, and Leu-enkephalin on perfusion medium flow rate in the intact perfused rat adrenal. Regul Pep 1994; 51: 55.CrossRefGoogle Scholar
  5. Nagatsu T. Genes for human catecholamine-synthesizing enzymes. Neurosci Res 1991; 12: 315.PubMedCrossRefGoogle Scholar
  6. Nativ O, Grant C S, Sheps S G, O’Fallon J R, Farrow G M, van Heerden J A, Lieber M M. The clinical significance of nuclear DNA pattern in 184 patients with pheochromocytoma. Cancer 1992; 69: 2683.Google Scholar
  7. Raum WJ. Pheochromocytoma. In: Bardin C W, ed. Current Therapy in Endocrinology and Metabolism, 5th ed. St. Louis, MO: Mosby, 1994: 172.Google Scholar

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© Springer Science+Business Media New York 1997

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  • William J. Raum

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