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The Biology of Neuropeptide Y and Related Peptides pp 457–509Cite as

Neuropeptide Y in Multiple Hypothalamic Sites Controls Eating Behavior, Endocrine, and Autonomic Systems for Body Energy Balance

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Part of the book series: Contemporary Neuroscience ((CNEURO))

Abstract

To survive, all animals must have sufficient nutrients available to maintain cellular metabolism and function. To ensure that these nutrients are continuously available, complex animals have neuronal systems that regulate food intake, energy storage, and energy expenditure. These regulatory systems control and coordinate the behavioral response (eating behavior), and numerous autonomic and endocrine responses to achieve energy balance. These systems are sensitive to and integrate inputs from a variety of food-related, environmental, humoral, and endocrine factors, which they in turn regulate, thus forming continuous feedback loops. Intensive research is focused on defining these systems in order to reveal general principles of neural integration and control, and to determine how dysfunctions of these mechanisms may contribute to, or even cause, some of the eating and body-weight disorders so prevalent in Western society.

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  1. B. Glenn Stanley
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  1. Department of Pharmacology, University of Alberta, Edmonton, Alberta, Canada

    William F. Colmers

  2. Department of Neurology, Cornell University Medical College, New York, NY, USA

    Claes Wahlestedt

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Stanley, B.G. (1993). Neuropeptide Y in Multiple Hypothalamic Sites Controls Eating Behavior, Endocrine, and Autonomic Systems for Body Energy Balance. In: Colmers, W.F., Wahlestedt, C. (eds) The Biology of Neuropeptide Y and Related Peptides. Contemporary Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-465-8_11

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