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Mammalian Cell-Cycle Responses to DNA-Damaging Agents

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DNA Damage and Repair

Part of the book series: Contemporary Cancer Research ((CCR))

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Abstract

DNA-damaging agents may shorten (29,110) or prolong the cell cycle, depending on the agent used, the dose, and the cell type. This chapter focuses on cell-cycle delays, since they are by far the most frequently observed cell-cycle response to DNA damage.

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  1. Roy Rowley
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  1. University of New Mexico, Albuquerque, NM, USA

    Jac A. Nickoloff

  2. Signal Pharmaceuticals, San Diego, CA, USA

    Merl F. Hoekstra

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Rowley, R. (1998). Mammalian Cell-Cycle Responses to DNA-Damaging Agents. In: Nickoloff, J.A., Hoekstra, M.F. (eds) DNA Damage and Repair. Contemporary Cancer Research. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-455-9_21

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  • DOI: https://doi.org/10.1007/978-1-59259-455-9_21

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