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The Natural History of CLL

Historical Perspective

  • Chapter
Chronic Lymphocytic Leukemia

Part of the book series: Contemporary Hematology ((CH))

Abstract

By convention, the history of chronic lymphocytic leukemia (CLL) begins in 1845, but it could be said to have started when the first white cells, “the globuli albicanates,” were noted by Joseph Lieutaud in 1749 (1). During the intervening years, many events have aided in our understanding of the etiology and treatment of CLL. In his discussion of the history of CLL, Rai (2) found it informative to define three eras: (1) the recognition of CLL as a clinical entity, 1845–1924; (2) initial clinical investigations, 1924–1973; and (3) the modern era, 1973–2002. We too have found this division informative and have grouped the events into those three periods.

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Authors
  1. Gerald E. Marti MD,PhD
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  2. Vincent Zenger PhD
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  1. Section of Hematology/Oncology, Veterans Affairs Medical Center, Augusta, GA, USA

    Guy B. Faguet MD

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Marti, G.E., Zenger, V. (2004). The Natural History of CLL. In: Faguet, G.B. (eds) Chronic Lymphocytic Leukemia. Contemporary Hematology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-412-2_1

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  • DOI: https://doi.org/10.1007/978-1-59259-412-2_1

  • Publisher Name: Humana Press, Totowa, NJ

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