Clinical Features of Parkinson’s Disease

  • Richard B. DeweyJr.
Part of the Current Clinical Practice book series (CCP)


Since James Parkinson’s original description of the shaking palsy in 1817, the classic clinical features of moderate-stage Parkinson’s disease (PD) have become widely known to physicians and even to the general public. Statistically speaking, most patients who present with resting tremor, slowing of movement, gait difficulty, and limb rigidity have idiopathic PD. When a typical resting tremor appears in the elderly, patients and their relatives may begin to suspect the diagnosis before a formal evaluation by a physician. Because treatments for the symptoms of PD abound today and putative “neuroprotective” agents are entering clinical trials, early diagnosis is essential.


Multiple System Atrophy Essential Tremor Postural Instability Progressive Supranuclear Palsy Normal Pressure Hydrocephalus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Selected Reading

  1. Caine DB, Snow BJ, Lee C. Criteria for diagnosing Parkinson’s disease. Ann Neurol 1992; 32 Suppl: S 125-S 127.CrossRefGoogle Scholar
  2. Dietz MA, Goetz CG, Stebbins GT. Evaluation of a modified inverted walking stick as a treatment for parkinsonian freezing episodes. Mov Disord 1990; 5: 243–247.PubMedCrossRefGoogle Scholar
  3. Hoehn MM, Yahr MD. Parkinsonism: onset, progression, and mortality. Neurology 1967; 17: 427–442.PubMedCrossRefGoogle Scholar
  4. Hughes AJ, Daniel SE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of idiopathic Parkinson’ s disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992; 55: 181–184.CrossRefGoogle Scholar
  5. Langston JW, Widner H, Goetz CG, Brooks D, Fahn S, Freeman T, Watts R. Core assessment program for intracerebral transplantations (CAPIT). Mov Disord 1992; 7: 2–13.PubMedCrossRefGoogle Scholar
  6. Parkinson J. An Essay on the Shaking Palsy. Printed by Whittingham and Rowland for Sherwood, Neely, and Jones, London, 1817.Google Scholar
  7. Stacy M, Jankovic J. Differential diagnosis of Parkinson’s disease and the parkinsonism plus syndromes. Neurol Clin 1992; 10: 341–359.PubMedGoogle Scholar
  8. Uitti RJ, Ahlskog JE, Maraganore DM, Muenter MD, Atkinson EJ, Cha RH, O’Brien PC. Levodopa therapy and survival in idiopathic Parkinson’ s disease: Olmsted County project. Neurology 1993; 43: 1918–1926.PubMedCrossRefGoogle Scholar
  9. Ward CD, Gibb WR. Research diagnostic criteria for Parkinson’s disease. Adv Neurol 1990; 53: 245–249.PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2000

Authors and Affiliations

  • Richard B. DeweyJr.

There are no affiliations available

Personalised recommendations