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Regulation of Cell Cycle and Apoptosis

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Cell Cycle Inhibitors in Cancer Therapy

Part of the book series: Cancer Drug Discovery and Development ((CDD&D))

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Abstract

The ancient Greeks believed that every life was subject to the whims of Fate or Moira, an inscrutable force that not even the gods could defy. Fate was often represented as three separate deities, the Moirae, who presided over the destiny of each life. Clotho spun the thread of life on her spool, Lakhesis measured it out, and Atropos cut the thread when a life had to end.

“But Fate, I tell you, no man can ever escape, Whether evil or noble, from the first moment of life.” (Iliad, Homer VI:488–489.)

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  1. Lucio Miele MD,PhD
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Editors and Affiliations

  1. Sbarro Institute for Cancer Research and Molecular Medicine, College of Science and Technology, Temple University, Philadelphia, PA, USA

    Antonio Giordano MD, PhD

  2. Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, PA, USA

    Kenneth J. Soprano PhD

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Miele, L. (2003). Regulation of Cell Cycle and Apoptosis. In: Giordano, A., Soprano, K.J. (eds) Cell Cycle Inhibitors in Cancer Therapy. Cancer Drug Discovery and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-401-6_5

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  • DOI: https://doi.org/10.1007/978-1-59259-401-6_5

  • Publisher Name: Humana Press, Totowa, NJ

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