Myocardial Infarction in the Younger Patient

  • James C. Fang
  • Jorge Plutzky
Part of the Contemporary Cardiology book series (CONCARD)


Coronary atherosclerosis in younger patients is quite common (1,2), and early evidence of this disease appears to be present in many, if not most, Americans by the age of 30 (3). Autopsy studies on casualties of both war and other trauma reveal early signs of atherosclerosis in up to 70% of individuals 30 yr old or younger, with significant flow-limiting stenoses in 10% (4). Recent intravascular ultrasound studies (IVUS) from cardiac transplant recipients also confirm these reports. In these studies, where the average donor age was 33.4 ± 13.2 yr, a remarkable 51.9% of the donor coronary arteries demonstrated IVUS evidence of atheroma when these arteries were examined soon after transplantation. Furthermore, in patients under the age of 20, an astonishing 17% had evidence of disease (5).


Fabry Disease Homocysteine Level Traditional Risk Factor Familial Hypercholesterolemia Premature Coronary Artery Disease 
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© Humana Press Inc., Totowa, NJ 2003

Authors and Affiliations

  • James C. Fang
  • Jorge Plutzky

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