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Microglia

Roles of Microglia in Chronic Neurodegenerative Diseases

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Neuroinflammation

Part of the book series: Contemporary Neuroscience ((CNEURO))

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Abstract

Over the last decade, the neuroinflammatory hypothesis of neurodegeneration has become well established. Our increased scientific understanding of the cascade(s) of events involved in chronic, slowly progressing neurodegenerative diseases has established the foundations for the first mechanistic drug discovery programs for the pharmacological treatment of these devastating diseases. An exciting feature of the neuroinflammatory hypothesis is that a target cell, microglia, has been identified for pharmacological approaches to halting or preventing slowly progressing neurodegenerative diseases.

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Wood, P.L. (2003). Microglia. In: Wood, P.L. (eds) Neuroinflammation. Contemporary Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-297-5_1

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