Angelica sinensis



A perennial of the UMBELLIFERAE family that grows to 50–250 cm. The stem is erect, often thick as an arm at the base, round, finely grooved, hollow, tinged reddish below and branched above. The leaves are very large, 60–90 cm and tri-pinnate with a hollow petiole, leaflets are ovate and unevenly serrate. The leaf sheaths are large and swollen. The flowers are greenishwhite to yellowish in 20–40 rayed compact umbels, no involucre; the tiny epicalyx has numerous sepals and the tips of the sepals are minute. The petals have indented, indistinguishable tips. The elliptic fruit is 7 mm long by 4 mm wide and winged. The outer fruit membrane separates from the inner one. The rhizome is short, fleshy and has long fibrous roots. The plant has a strong tangy odor; taste is sweetish to burning tangy.


Ferulic Acid Water Extract Panax Ginseng Crude Drug Curcuma Longa 
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  1. ASO100.
    Schmidt, C. F., B. E. Read and K. K. Chen. Chinese drugs. I. Tang-kwei. Chin Med J 1924; 38: 362.Google Scholar
  2. ASO101.
    Anon . The Atlas of Commonly Used Chinese Traditional Drugs, Revolutionary Committee of the Inst Materia Medica, Chinese Acad Sci, Peking, 1970.Google Scholar
  3. AS0102.
    Matsui, A. D. S., J. Rogers, Y. K. Woo and W. C. Cutting. Effects of some natural products on fertility in mice. Med Pharmacol Exp 1967; 16: 414.Google Scholar
  4. AS0103.
    Ibragimova, F. I. and V. S. Ibragimova. Principal Remedies of Chinese Medicine. Foreign Technology Div, Air Force Systems Command, Wright-Patterson Air Force Base, Ohio, 1964.Google Scholar
  5. AS0104.
    Read, B. E. Some of the old Chinese drugs used in obstetrical practice. J Obstet Gynecol Brit Emp 1927; 34: 498–508.CrossRefGoogle Scholar
  6. AS0105.
    Li, C. P. Chinese Herbal Medicine. U. S. Dept. Health, Education and Welfare, Publ. No. (NIH) 75–732, Washington, D. C., 1974.Google Scholar
  7. AS0106.
    Ch’en, W. C., C. H. Sun, H. Y. Li and K. S. Ting. Studies on antihypertensive drugs. Hypotensive effect and toxicity of er hsien t’ang. Chin Med J 1962; 81(5): 295–302.Google Scholar
  8. ASO107.
    Chen, Y., H. Zhang, N. Chen, T. Zhao and M. Wang. Analysis of the ingredients of Angelica sinensis-Determination of the structure of angelicide. K’o Heush T’ung Pao (Foreign Lang Ed) 1984;29(4): 560–562.Google Scholar
  9. AS0108.
    Hon, P. M., C. M. Lee, T. F. Choang, K. Y. Chui and H. N. C. Wong. A ligustilide dimer from Angelica sinensis. Phytochemistry 1990; 29(4): 1189–1191.CrossRefGoogle Scholar
  10. AS0109.
    Kane, J. A., S. P. Kane and S. Jain. Hepatitis induced by traditional Chinese herbs; possible toxic components. Gut 1995; 36(1): 146–147.CrossRefGoogle Scholar
  11. ASO110.
    Wang, Y. P. and B. Zhu. The effect of angelica polysaccharide on proliferation and differentiation of hematopoietic precursor cells. Zhonghua Yixue Zazhi 1996; 76(5): 363–366.Google Scholar
  12. ASO111.
    Kong, Y. C., S. Y. Hu, F. K. Lau, C. T. Che, H. W. Yeung, S. Cheung and J. C. C. Hwang. Potential anti-fertility plants from Chinese medicine. Amer J Chinese Med 1976;4: 105–128.CrossRefGoogle Scholar
  13. AS0112.
    Lin, M., G. Zhu, Q. M. Sun and Q. C. Fang. Chemical studies of Angelica sinensis. Yao Hsueh Hsueh Pao 1979; 14(9): 529–534.Google Scholar
  14. AS0113.
    Chou, Y. P., L. Y. Huang, Y. L. Cheng, L. L. Fap, L. Y. Chang and K. Y. Tseng. The effect of Angelica sinensis on hemodynamics and myocardiac oxygen consumption in dogs. Yao Hsueh Hsueh Pao 1979; 14: 156–160.Google Scholar
  15. AS0114.
    Fang, H. J., R. M. Lu, G. S. Lin and T. C. Liu. Studies on the components of essential oils. Yao Hsueh Hsueh Pao 1979; 14(10): 617–623. Google Scholar
  16. AS0115.
    Huang, M. F., W. J. Hang and Q. Zhong. Hair growth stimulating preparations containing medicinal plant extracts. Patent-Faming Zhuanli Shenqing Gongkai Shuomingshu-1,043,624 1990; 6 pp.Google Scholar
  17. AS0116.
    Hong, C. Y., J. Ku and P. Wu. Astragalus membranaceus stimulates sperm motility in vitro. Amer J Chinese Med 1992; 20 (3/4): 289–294.CrossRefGoogle Scholar
  18. AS0117.
    Lay, H. L., W. Y. Lin, Y. Motota, F. Tamai and T. Tanabe. Studies on the production and the improvement in quality of Angelica acutiloba Kitagawa. II. Seasonal variation on plant growth, yield, extract ligustilide contents in different species of crude drug “tou-ki”. Shoyakugaku Zasshi 1992; 46(4): 365–371.Google Scholar
  19. AS0118.
    Horii, A. and M. Maekewa. Clinical evaluation of ginseng and astragalus combination used to treat nephroptosis. Int J Orient Med 1993: 18(3): 140–147.Google Scholar
  20. AS0119.
    Wang, H. Y., J. Z. Li, S. L. Zhu, H. Yu, S. F. Mao and M. H. Zhang. Effects of Tripterygium wildordii, Astragalus membranaceus and Angelica sinensis on glomerular permeability in rats with puromycin nephrosis. Chunghua I Hsueh Tsa chih (Beijing) 1988; 68(9): 513–515.Google Scholar
  21. AS0120.
    Choy, Y. M., K. N. Leung, C. S. Cho, C. K. Wong and P. K. T. Pang. Immunopharmacological studies of low molecular weight polysaccharide from Angelica sinensis. Amer J Chinese Med 1994: 22(2): 137–145.CrossRefGoogle Scholar
  22. AS0121.
    Sugiyama, K., H. Ueda, Y. Suhara, Y. Kajima, Y. Ichio and M. Yokota. Protective effect of sodium 1-malate, an active constituent isolated from Angelica radix, on cis-diamminedichloroplatinum (II)-induced toxic side effect. Chem Pharm Bull 1994; 42(12): 2565–2568.CrossRefGoogle Scholar
  23. AS0122.
    Yin, X. J., D. X. Liu, H. Wang and Y. Zhou. A study on the mutagenicity of 102 raw pharmaceuticals used in Chinese traditional medicine. Mutat Res 1991; 260 (1): 73–82.CrossRefGoogle Scholar
  24. AS0123.
    Duke, J. A. and E. S. Ayensu. Medicinal Plants of China. Reference Publications, Inc. Algonac, Michigan 1985; 1(4): 352–361.Google Scholar
  25. AS0124.
    Park, C. H., S. H. Kim, W. Choi, Y. J. Lee, J. S. Kim, S. S. Kang and Y. H. Suh. Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa. Planta Med 1996; 62(5): 405–409.CrossRefGoogle Scholar
  26. AS0125.
    Tanaka, S., C. Hoshino, Y. Ikeshiro, M. Tabata and M. Konoshima. Studies on anti-nociceptive activities of aqueous extracts from different varieties of toki. Yakugaku Zasshi 1977; 97: 14.Google Scholar
  27. AS0126.
    Lucas, R. Secrets of the Chinese Herbalists. Parker Publ. Co. New York, 1977.Google Scholar
  28. AS0127.
    Lu, R. M., L. I. Ho and S. Y. Lo. Determination of ferulic acid in danggui (Angelica sinensis). Chung Ts’ao Yao 1980; 11(9): 395–398.Google Scholar
  29. AS0128.
    Sheu, S. J., Y. S. Ho, Y. P. Chen and H. Y. Hsu. Analysis and processing of Chinese herbal drugs: VI. The study of Angelica radix. Planta Med 1987; 53(4): 377–378.CrossRefGoogle Scholar
  30. AS0129.
    Gu, Y. X., Y. F. Cui, Z. P. Wang and X. T. Liu. Effect of plant polysaccharides on T and B lymphocytes in normal and tumor transplanted mice. J Trad Chin Med 1988; 8(3): 198–202.Google Scholar
  31. AS0130.
    Ma, L. F., X. M. Mao, X. W. Li and H. S. Zhao. The effect of Angelica sinensis polysaccharides on mouse bone marrow hematopoieses. Zhongua Xinxueguanbing Zazhi 1988; 9(3): 148–149.Google Scholar
  32. AS0131.
    Yu, L. A. and Q. L. Xu. Treatment of infectious hepatitis with an herbal decoction. Phytother Res 1989; 3(3): 13–14.Google Scholar
  33. AS0132.
    Tuch, B. E., K. A. Lenord and J. F. Thompson. Evidence that Chinese herbal medicine is of no advantage in murine fetal pancreatic transplants. Transplantation 1989; 4792: 407–408.Google Scholar
  34. AS0133.
    Watanabe, K. I., K. Suzuki, F. Masani, Y. Horokawa, A. Shibata and S. Maruyama. Effect of tokishakuyaku-san on the fetal development of spontaneously hypertensive rats. Acta Med Biol 1989; 37(2): 91–95.Google Scholar
  35. AS0134.
    Fukushima, M., H. Kuroda and Y. Inaoka. A study of crude drugs for the development of an effective component in cosmetics (II) Effect of crude drug extractives on the size of auricular sebaceous glands in hamsters. Shoyakugaku Zasshi 1989; 43(4): 305–309.Google Scholar
  36. AS0135.
    Zhang, H., Z. X. Li and Y. Z. Chen. Studies of the active principles of Angelica sinensis (Oliv.). Diels-isolation, characterization and biological effect of its polysaccharides. Lan-chou Ta Hsueh Hsueh Pao, Tsu Jan K’o Hsueh Pan 1989; 25(4): 78–81.Google Scholar
  37. AS0136.
    Van Benschoten, M. M. Management of systemic fungal infections with Chinese herbal medicine. Int J Orient Med 1990; 15(3): 141–145.Google Scholar
  38. AS0137.
    Han, G. Q., J. X. Pan, C. L. Li and F. Tu. The screening of Chinese traditional drugs by biological assay and the isolation of some active components. Int J Chinese Med 1991; 16(1): 1–17.Google Scholar
  39. AS0138.
    Chen, S. M., Y. M. Lu, X. M. Yan, G. H. Hu, H. M. Zhu and H. Xie. Production of superoxide radical and its interaction with natural medicine. Fu-tan Hsueh Pao, Tsu Jan K’o Hsueh 1991; 30(1): 31–36.Google Scholar
  40. AS0139.
    Yu, L. A. Letter to the editor. Phytother Res 1987; 1(4): 11.Google Scholar
  41. AS0140.
    Imamichi, T., K. Hayashi, T. Nakamura, K. Kaneko and J. Koyama. A Chinese traditional medicine, juzentaihoto, inhibits the 02-generation by macrophages. J Pharmacobio Dyn 1989; 12(11): 693–699.CrossRefGoogle Scholar
  42. AS0141.
    Rao, G. X., X. J. Yu and H. D. Sun. Chemical constituents of “lang-du dang-gui” (Angelicasp.). Yun-nan Chih Wu Yen Chiu 1991; 13(1): 85–88.Google Scholar
  43. AS0142.
    Me, Q. B., J. Y. Tao and B. Cui. Advances in the pharmacological studies of Radix angelica sinensis (Oliv) diels (Chinese danggui). Chin Med J 1991; 104(9): 776–781.Google Scholar
  44. AS0143.
    Mase, A., H. Ono, H. Nagai and T. Eda. Effect of tang-kuei and gardenia combination on immunological reaction. International J Oriental Medicine1992; 17(1): 23–26.Google Scholar
  45. AS0144.
    Zhang, Y. S., M. X. Zhou, Z. D. Yao and N. H. Peng. Treatment of 70 cases of psoriasis with qufeng xuanwei mixture. Xinjiang J Trad Chin Med 1987; 1987 (2): 26–28.Google Scholar
  46. AS0145.
    Yan, T. Y., A. C. Hou, G. Y. Zhou, M. M. Gong, Z. M. Li, X. N. Wu and B. T. Sun. Pharmacological effects of Angelica injection and its treatment of infantile viral pneumonia. Chin J Integ Trad West Med 1987; 7(3): 161–162.Google Scholar
  47. AS0146.
    Liu, D. X., X. J. Yin, H. C. Wang, Y. Zhou and Y. H. Zhang. Antimutagenicity screening of water extracts from 102 kinds of Chinese medicinal herbs. Chungkuo Chung Yao Tsa Chi Li 1990; 15(10): 617–622.Google Scholar
  48. AS0147.
    Gun, R., J. Csg Lu and Y. M. Xu. Phospholipid components of danggui. Zhongguo Zhongyao Zazhi 1991; 16(12): 741–742.Google Scholar
  49. AS0148.
    Ma, W. C. Comparison of the constituents between gansu and cultivated dangguei (Angelica sinensis). Chung Ts’ao Yao 1980; 11: 443.Google Scholar
  50. AS0149.
    Yin, Z. Z., L. Y. Zhang and L. N. Xu. The effect of dang-gui (Angelica sinensis) and its ingredient ferulic acid on rat platelet aggregation and release of 5-HT. Yao Hsueh Hsueh Pao 1980; 15: 321–326.Google Scholar
  51. AS0150.
    Xu, L. N., O. Y. Rong, Z. Z. Yin, L. Y. Zhang and L. X. Ji. The effect of dang-gui (Angelica sinensis) and its constituent ferulic acid on phagocytosis in mice. Yao Hsueh Hsueh Pao 1981; 16: 41–414.Google Scholar
  52. AS0151.
    Masamoto, Y., S. Iida and M. Kuto. Inhibitory effect of Chinese crude drugs on tyrosinase. Planta Med 1980; 40: 361–365.CrossRefGoogle Scholar
  53. AS0152.
    Chen, Y. M. Observation of 737 cases of impotence treated by “kang-wei-ling” (potency arousing). Chung I Tsa Chih 1981; 22(4): 36–37.Google Scholar
  54. AS0153.
    Zhu, F. Q., W. J. Zhang and J. X. Xu. Experience of treating 42 cases of ectopic pregnancy by the method of combining TCM and Western medicine. Zhejiang-Zhongyi Zazhi 1982; 17: 102.Google Scholar
  55. AS0154.
    Dai, S. J. And Y. H. Chen. Healing of ten-year amenorrhea with traditional herbal drugs. Shanghai chung I Tsa Chih 1982; 1982(5): 17.Google Scholar
  56. ASO155.
    Wong, H. B. Effects of herbs and drugs during pregnancy and lactation. J Singapore Pediatric Soc 1979; 21(3/4): 169–178.Google Scholar
  57. AS0156.
    Pong, J. J., W. F. Wang, T. F. Lee and W. Liu. Effect of 28 herbal drugs on the uptake of 86-RU by mouse heart muscle. Chung Ts’ao Yao 1981; 12(1): 33–34.Google Scholar
  58. AS0157.
    Wang, K. R., Y. L. Zhao, D. S. Wang and M. L. Zhao. Effects of traditional Chinese herbs, toad tincture and adenosine 3′, 5′ camp on Ehrlich ascites tumor cells in mice. Chin Med J 1982; 95(7): 527–532.Google Scholar
  59. AS0158.
    Wang, X. H. A report on 60 cases of functional uterine hemorrhage treated with “xian he gu gong tang” (decoction of agrimony and others). Zhejiang Zhongyi Zazhi 1982; 17: 272.Google Scholar
  60. AS0159.
    Chen, Y. Z., Z. X. Duan, H. D. Zhang, J. Y. Tao, Y. P. Ruan, Q. B. Mei, S. Liu, Q. D. Tian, F. X. Xie and Y. F. Yu. Chemical composition and pharmacological effects of Angelica sinensis (Oliv) Diels. Lan-chou Ta Hsueh Hsueh Pao, Tsu Jan K’o Hsueh Pan 1984; 20(1): 158–160.Google Scholar
  61. AS0160.
    Chen, Y. Z., H. D. Zhang and W. T. Cai. Study on the analysis of chemical constituents of Angelica sinensis. III. Determination of amino acids in min-gui. Lanchou Ta Hsueh Hsueh Pao, Tsu Jan K’o Hsueh Pan 1983; 19: 194–195.Google Scholar
  62. AS0161.
    Ma, E., C. Luo, C. Huang and F. Liu. The treatment of severe hemorrhage of the gastrointestinal tract in burn children by combined traditional Chinese and Western medicine. Chung I Tsa Chih (Engl Ed) 1983; 3(1): 59–61.Google Scholar
  63. AS0162.
    Chen, K. Certain progress in the treatment of coronary heart disease with traditional medicinal plants in China. Amer J Chinese Med 1981; 9: 193–196.CrossRefGoogle Scholar
  64. AS0163.
    Cha, L., C. C. Chien and F. H. Lu. Antiarrhythmic effect of Angelica sinensis root, tetrandrine and Sophora flavescens root. Yao Hsueh T’ung Pao 1981; 16(4): 53–54.Google Scholar
  65. AS0164.
    Chen, B. X., R. G. Jiang and J. K. Hu. Traditional Chinese medicine action on experimental rat goiter and normal rat thyroids. Chin Med J 1983; 96(3): 235–239.Google Scholar
  66. AS0165.
    Terasawa, K., A. Imadays, H. Tosa, T. Mitsuma, K. Toriizura, K. Takeda, M. Mikage, M. Hattori and T. Namba. Chemical and clinical evaluation of crude drugs derived from Angelica acutilobae and A. Sinensis. Fitoterapia 1985; 56(4): 201–208.Google Scholar
  67. AS0166.
    Han, J. and F. Li. Clinical observations on the efficacy of qiang gan ruan jian tang in the treatment of 105 cases of uncompensated cirrhosis of the liver. Natl Med J China 1979; 59: 584–588.Google Scholar
  68. AS0167.
    Han, J. H. and F. G. Li. A study on experimental hepatic cirrhosis treated with qiang gan ruan jian tang (a Chinese herbal decoction). Natl Med J China 1979; 59: 577–583.Google Scholar
  69. AS0168.
    Ma, X. Effect of Salvia miltiorrhiza on experimental hepatic regeneration. Chin J Integ Trad West Med 1983;3(3): 182–185.Google Scholar
  70. AS0169.
    Liu, X. L. Twelve cases of aplastic anemia treated mainly by ready made Chinese drugs. Chung I Tsa Chih 1984; 25 (10): 759–760.Google Scholar
  71. AS0170.
    Kou, W., Z. Chen and S. Tao. Clinical effect of “yi gi huo xue” medicinal herbs in acute myocardial infarction: A randomized controlled study. Chin J Integ Trad West Med 1983; 3(3): 146–148.Google Scholar
  72. AS0171.
    Siang, S. T. Use of combined traditional Chinese and Western medicine in the management of burns. Panminerva Med 1983; 25(3): 197–202.Google Scholar
  73. AS0172.
    Zhu, D. P. Q. Dong quai. Amer J Chinese Med 1987; 15(3/4): 117–125.CrossRefGoogle Scholar
  74. AS0173.
    Yanfg, L. L., K. Y. Yen, Y. Kiso and H. Kikino. Antihepatotoxic actions of Formosan plant drugs. J Ethnopharmacol 1987; 19(1): 103–110.CrossRefGoogle Scholar
  75. AS0174.
    Koda, A., Y. Ono, T. Nishiyori, H. Nagai, N. Matsuura, A. Mase and T. Matsuyama. Immunopharmacological studies of wen-qingyin, a Chinese blended medicine: Effects on type IV allergic reactions and humoral antibody production. Int J Immunopharmacol 1987; 9(3): 289–295.CrossRefGoogle Scholar
  76. AS0175.
    Kawashiri, N., K. Torizuka, I. Adachi, M. Ueno, K. Terasawa and I. Horikoshi. Effects of traditional crude drugs on fibrinolysis by plasmin: Antiplasmin principles in eupolyphaga. Chem Pharm Bull 1986; 34(6): 2512–2517.CrossRefGoogle Scholar
  77. AS0176.
    He, Z. P. Clinical studies on deficient type amenorrhea treated by regulating menstruation decoction of Radix angelica sinensis and Radix astragaliseu Hedysari (dang gui-huang qi). Chung I Tsa Chih 1984; 25(12): 915–917.Google Scholar
  78. AS0177.
    Fu, Y. F., Y. Xia, Y. P. Shi and N. Q. Sun. Treatment of 34 cases of infertility due to tubal occlusion with compound danggui injection by irrigation. Jiangsu J Trad Chin Med 1988; 9(1): 15–16.Google Scholar
  79. AS0178.
    Xiong, X., Y. Zhang, Q. Y. Zai, H. S. Luo, S. B. Li and J. Y. Guo. The protective effect of Radix angelicae sinensis against acute liver damage by d-galactosamine in rats: A histochemical study. Wu-han I Hsueh Yuan Hsueh Pao 1982; 11(4): 68–72.Google Scholar
  80. AS0179.
    Li, F. K. Problems concerning artificial abortion through oral administration of traditional drugs. Ha-Erh-Pin Chung-I 1965; 1965 (1): 11–14.Google Scholar
  81. AS0180.
    Lin, C. S. Enriched “four-ingredient brew” to treat in situ dead fetus. Fu-Chien Chung-I-Yoo 1964: 1964(1): 44–45.Google Scholar
  82. AS0181.
    Wu, D. Y. Treatment of 136 cases of uterine mycoma with ‘Kung Ching Tang’. Chung I Tsa Chih 1981; 22(1): 34–35.Google Scholar
  83. AS0182.
    Chen, H. P., S. X. Liu, G. M. Li and Q. H. Li. Determination of ferulic acid in the Chinese angelica (Angelica sinensis) and its preparations by HPLC. Chung Ts’ao Yao 1989; 19(10): 447–448.Google Scholar

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