Abstract
The clinician should attempt to understand any platelet count increased above the normal range of values and confirmed on two blood tests. One pitfall in leaving chronic thrombocytosis unexplained is the later development of a thrombotic complication and an oversight in the diagnosis of an underlying myeloproliferative disorder.
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Buss DH, O’Connor ML, Woodruff RD, Richards FII, Brockschmidt JK. Bone marrow and peripheral blood findings in patients with extreme thrombocytosis. A report of 63 cases. Arch Pathol Lab Med 1991; 115: 475–480.
Cortelazzo S, Finazzi G, Ruggeri M, Vestri O, Galli M, Rodeghiero F, Barbui T. Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis. N Engl J Med 1995; 332: 1132–1136.
Kessler CM, Klein HG, Havlik RJ. Uncontrolled thrombocytosis in chronic myeloproliferative disorders. Br J Haematol 1982; 50: 157–167.
Messinezy M, Pearson TC. ABC of clinical haematology. Polycythaemia, primary (essential) thrombocythaemia and myelofibrosis. BMJ 1997: 314: 587–590.
Michiels JJ, van Genderen PJ, Lindemans J, van Vliet HH. Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia. Leuk Lymphoma 1996: 22 Sunpl 1: 47–56.
Murphy S, Peterson P, Iland H, Laszlo J. Experience of the Polycythemia Vera Study Group with essential thrombocythemia: a final report on diagnostic criteria, survival, and leukemic transition by treatment. Semin Hematol 1997; 34: 29–39.
Ravandi-Kashani F, Schafer AI. Microvascular disturbances, thrombosis, and bleeding in thrombocythemia: current concepts and perspectives. Semin Thromb Hemost 1997: 23: 479–488.
Tefferi A, Silverstein MN, Hoagland HC. Primary thrombocythemia. Semin Oncol 1995; 22: 334–340.
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Solberg, L.A. (2001). Differential Diagnosis and Management of Thrombocytosis. In: Tefferi, A. (eds) Primary Hematology. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-228-9_9
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DOI: https://doi.org/10.1007/978-1-59259-228-9_9
Publisher Name: Humana Press, Totowa, NJ
Print ISBN: 978-1-61737-122-6
Online ISBN: 978-1-59259-228-9
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