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Low Birth Weight and Perinatal Mortality

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Part of the Nutrition ◊ and ◊ Health book series (NH)

Abstract

It is widely recognized that weight at birth is an important indicator of fetal and neonatal health for both individuals and populations. Birth weight in particular is strongly associated with fetal, neonatal, and postneonatal mortality; infant and childhood morbidity; and long-term growth and development (1,2). According to the World Bank/World Health Organization (WHO) study of the global burden of disease, low birth weight (LBW) and other perinatal causes are a leading cause of death and disability (3). Of the 2.44 million global deaths resulting from perinatal causes, 97% occur in developing country settings. Thus LBW and perinatal mortality are public health problems of crucial importance in such settings.

Keywords

  • Preterm Birth
  • Gestational Weight Gain
  • Perinatal Mortality
  • Emergency Obstetric Care
  • Early Neonatal Death

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. McCormick MC. The contribution of low birth weight to infant mortality and childhood morbidity. N Engl J Med 1985; 312: 82–90.

    CrossRef  CAS  Google Scholar 

  2. World Health Organization (WHO). Physical Status: The Use and Interpretation of Anthropometry. WHO Technical Report Series No. 854. Geneva: WHO, 1995.

    Google Scholar 

  3. Murray CJL, Lopez AD, eds. The Global Burden of Disease: A Comprehensive Assessment of Mortality and Disability from Diseases, Injuries, and Risk Factors in 1990. Cambridge, MA: Harvard University Press, 1996.

    Google Scholar 

  4. WHO. Prevention of perinatal morbidity and mortality. WHO Technical Report Series No. 457. Geneva: WHO, 1970.

    Google Scholar 

  5. Kramer MS. Determinants of low birth weight: methodological assessment and meta-analysis. Bull WHO 1987; 65: 663–737.

    CAS  Google Scholar 

  6. Williams RL, Creasy RK, Cunningham GC, Hawes WE, Norris FD, Tashiro M. Fetal growth and perinatal viability in California. Obset Gynecol 1982; 59: 624–632.

    CAS  Google Scholar 

  7. Hogue CJR, Buehler JW, Strauss LT, Smith JC. Overview of the National Infant Mortality Surveillance (NIMS) project: design, methods, results. Public Health Rep 1987; 102: 126–138.

    CAS  Google Scholar 

  8. Villar J, Belizan JM. The relative contribution of prematurity and fetal growth retardation to low birth weight in developing and developed societies. Am J Obstet Gynecol 1982; 143: 793–798.

    CAS  Google Scholar 

  9. de Onis M, Habicht JP. Anthropometric reference data for international use: recommendations from a World Health Organization Expert Committee. Am J Clin Nutr 1996; 64: 650–658.

    Google Scholar 

  10. Blackmore CA, Savitz DA, Edwards LJ, Harlow SD, Bowes WA. Racial differences in the patterns of preterm delivery in central North Carolina, USA. Paediatr Perinat Epidemiol 1995; 9: 281–295.

    CrossRef  CAS  Google Scholar 

  11. Goldenberg RL, Cliver SP, Mulvihill FX, Hickey CA, Hoffman HJ, Klerman LV, Johnson MJ. Medical, psychosocial, and behavioral risk factors do not explain the increased risk for low birth weight among black women. Am J Obstet Gynecol 1996; 175: 1317–1324.

    CrossRef  CAS  Google Scholar 

  12. Parker JD, Schoendorf KC, Kiely JL. Associations between measures of socioeconomic status and low birth weight, small for gestational age, and premature delivery in the United States. Ann Epidemiol 1994; 4: 271–278.

    CrossRef  CAS  Google Scholar 

  13. McCormick MC. The contribution of low birth weight to infant mortality and childhood morbidity. N Engl J Med 1985; 312: 82–90.

    CrossRef  CAS  Google Scholar 

  14. Committee to Study the Prevention of Low Birthweight, Division of Health Promotion and Disease Prevention, Institute of Medicine. Preventing Low Birthweight. Washington, DC: National Academy Press, 1985.

    Google Scholar 

  15. Dollfus C, Paletta M, Siegel E, Cross AW. Infant mortality: a practical approach to the analysis of the leading causes of death and risk factors. Pediatrics 1990; 86: 176–183.

    CAS  Google Scholar 

  16. Morrison JC. Preterm birth: a puzzle worth solving. Obstet Gynecol 1990; 76 (Suppl): 5S–12S.

    CAS  Google Scholar 

  17. Barker DJP. Fetal and Infant Origins of Adult Disease. BMJ Publishing Group, London, UK, 1992.

    Google Scholar 

  18. Dubowitz LMS, Dubowitz V, Goldberg C. Clinical assessment of gestational age in the newborn infant. J Pediatr 1970; 77: 1–10.

    CrossRef  CAS  Google Scholar 

  19. Ballard JL, Novak KK, Driver M. A simplified score for assessment of fetal maturation of newly born infants. J Pediatr 1979; 95: 769–774.

    CrossRef  CAS  Google Scholar 

  20. Capurro H, Konichezky S. Fonseca D. Caldeyro-Barcia R. A simplified method for diagnosis of gestational age in the newborn infant. J Pediatr 1978; 93: 120–122.

    CrossRef  CAS  Google Scholar 

  21. Spinnato JA, Sibai BM, Shaver DC, Anderson GD. Inaccuracy of Dubowitz gestational age in low birth weight infants. Obstet Gynecol 1984; 63: 491–495.

    CAS  Google Scholar 

  22. Alexander GR, de Caunes F, Hulsey TC, Tompkins ME, Allen M. Validity of postnatal assessments of gestational age: comparison of the method of Ballard et al. and early ultrasonography. Am J Obstet Gynecol 1992; 166: 891–895.

    CrossRef  CAS  Google Scholar 

  23. Donovan EF, Tyson JE, Ehrenkranz RA, Verter J, Wright LL, Korones SB, et al. for the National Institute of Child Health and Human Development Neonatal Research Network. Inaccuracy of Ballard scores before 28 weeks’ gestation. J Pediat 1999; 135: 147–152.

    CrossRef  CAS  Google Scholar 

  24. Balcazar H, Haas J. Classification schemes of small-for-gestational age and type of intrauterine growth retardation and its implications to early neonatal mortality. Early Hum Dev 1990; 24: 219–230.

    CrossRef  CAS  Google Scholar 

  25. Ashworth A. Effects of intrauterine growth retardation on mortality and morbidity in infants and young children. Eur J Clin Nutr 1998; 52: S34–S42.

    CrossRef  Google Scholar 

  26. Banos FC, Hutly SRA, Victora CG, Kirkwood BR, Vaughan JP. Comparison of the causes and consequences of prematurity and intrauterine growth retardation: longitudinal study in Southern Brazil. Pediatrics 1992; 90: 238–244.

    Google Scholar 

  27. Gardosi J, Mul T, Mongelli M, Fagan D. Analysis of birthweight and gestational age in antepartum stillbirths. Br J Obstet Gynaecol 1998; 105: 524–530.

    CrossRef  CAS  Google Scholar 

  28. Cnattingius S, Haglund B, Kramer MS. Differences in late fetal death rates in association with determinants of small for gestational age fetuses: population based cohort study. BMJ 1998; 316: 1483–1487.

    CrossRef  CAS  Google Scholar 

  29. Modanlou, HD, Dorchester WL, Thorosian A, Freeman RK. Macrosomia-maternal, fetal, and neonatal implications. Obstet Gynecol 1980; 55: 420–424.

    CAS  Google Scholar 

  30. Boyd, ME, Usher RH, Mclean FH. Fetal macrosomia: prediction, risks, proposed management. Obstet Gynecol 1983; 61: 715–722.

    CAS  Google Scholar 

  31. Govindasamy P, Stewart MK, Rutstein SO, Boerma JT, Sommerfelt AE. High-Risk Births and Maternity Care. Demographic and Health Survey. Comparative Studies No. 8. Calverton, MD: DHS, 1993. Webmaster@mail.medscape.com

    Google Scholar 

  32. Ferraz EM, Gray RH. A case-control study of stillbirths in Northeast Brazil. Intl J Gynecol Obstet 1990; 34: 13–19.

    CrossRef  Google Scholar 

  33. Escoffery C, Greenwood R, Ashley D, Coard K, Keeling J, Golding J. Deaths associated with intrapartum asphyxia in Jamaica. Paediatr Perinat Epidemiol 1994; 8 (suppll): 119–142.

    CrossRef  Google Scholar 

  34. Perera T, Lwin KM. Perinatal mortality and morbidity including low birthweight: a South-East Asia regional profile. SEARO Regional Health Papers No. 3. 1984.

    Google Scholar 

  35. Victora CG, Barros FC, Vaughan PJ, Texeira AMB. Birthweight and infant mortality: a longitudinal study of 5914 Brazilian children. Intl J Epidimiol 1987; 16 (2): 239–245.

    CrossRef  CAS  Google Scholar 

  36. Samms-Vaughan ME, McCaw-Binns AM, Ashley DC, Foster-Williams K. Neonatal mortality determinants in Jamaica. J Trop Pediatr 1990; 36: 171–175.

    CrossRef  CAS  Google Scholar 

  37. Gray RH, Ferraz EM, Amorim MS, De Melo LF. Levels and determinants of early neonatal mortality in natal northeastern Brazil: results of a surveillance and case-control study. Intl J Epidemiol 1991; 20: 467–473.

    CrossRef  CAS  Google Scholar 

  38. WHO. Maternal anthropometry and pregnancy outcomes: WHO Collaborative Study. Bull WHO 1995; 73(suppl):l-98.

    Google Scholar 

  39. Govindasamy P, Stewart MK, Rutstein SO, Boerma JT, Sommerfelt AE. United Nations Children’s Fund. The State of the World’s Children 1997. Oxford: Oxford University Press, 1997.

    Google Scholar 

  40. Cook JD, Alvarado J, Gutnisky A, Jamra M, Labardini J, Layrisse M, et al. Nutritional deficiency and anemia in Latin America: a collaborative study. Blood 1971; 38: 591–603.

    CAS  Google Scholar 

  41. Yusufji D, Mathan VI, Baker SJ. Iron, folate, and vitamin B12 nutrition in pregnancy: a study of 1000 women from southern India. Bull WHO 1973; 48: 15–22.

    CAS  Google Scholar 

  42. Cavdar AO, Babacan E, Arcasoy A, Ertem U. Effect of nutrition on serum zinc concentration during pregnancy in Turkish women. Am J Clin Nutr 1980; 33: 542–544.

    CAS  Google Scholar 

  43. Baker SJ. Nutritional Anaemias: Part 2: tropical Asia. Clin Haematol 1981; 10: 843–871.

    CAS  Google Scholar 

  44. WHO. The Prevalence of Anaemia in Women: A Tabulation of Available Information, 2nd ed. WHO/MCH/MSM, 92. 2. Geneva: WHO, 1992.

    Google Scholar 

  45. Kirksey A, Wachs TD, Yunis F, Srinath U, Rahmanifar A, McCabe G, et al. Relation of maternal zinc nutriture to pregnancy outcome and infant development in an Egyptian village. Am J Clin Nutr 1994; 60: 782–792.

    CAS  Google Scholar 

  46. Gillespie S. Major issues in the control of iron deficiency. Ottawa: Micronutrient Initiative/UNICEF, 1998.

    Google Scholar 

  47. Subcommittee on Diet, Physical Activity, and Pregnancy Outcome, Food and Nutrition Board, U.S. Institute of Medicine/National Academy of Sciences. Diet and Activity During Pregnancy and Lactation. In: Nutrition Issues in Developing Countries. Washington, DC: National Academy Press, 1992.

    Google Scholar 

  48. Ceesay SM, Prentice AM, Cole TJ, Foord F, Weaver LT, Poskitt EME, et al. Effects on birth weight and perinatal mortality of maternal dietary supplements in rural Gambia: 5 year randomised controlled trial. BMJ 1997; 315: 786–790.

    CrossRef  CAS  Google Scholar 

  49. Mahomed K. Routine iron supplementation during pregnancy [Cochrane review]. In: Pregnancy and childbirth module of the Cochrane Database of Systematic Reviews. Neilson JP, Crowther CA, Hodnett ED, Hofmeyr GJ, eds. The Cochrane Library, Issue 4, Oxford: Update Software, 1999.

    Google Scholar 

  50. Mahomed K. Routine folate supplementation in pregnancy [Cochrane review]. In: Pregnancy and childbirth module of the Cochrane Database of Systematic Reviews. Neilson JP, Crowther CA, Hodnett ED, Hofmeyr GJ, eds. The Cochrane Library, Issue 4, Oxford: Update Software, 1999.

    Google Scholar 

  51. Mahomed K. Zinc supplementation in pregnancy [Cochrane review]. In: Pregnancy and childbirth module of the Cochrane Database of Systematic Reviews. Neilson JP, Crowther CA, Hodnett ED, Hofmeyr GJ, eds. The Cochrane Library, Issue 2, Oxford: Update Software, 1998.

    Google Scholar 

  52. Levine RJ, Hauth JC, Curet LB, Sibai BM, Catalano PM, Morris CD, et al. Trial of calcium to prevent preeclampsia. N Engl J Med 1997; 337: 69–76.

    CrossRef  CAS  Google Scholar 

  53. Kesmodel U, Olsen SF, Salvig JD. Marine n-3 fatty acid and calcium intake in relation to pregnancy induced hypertension, intrauterine growth retardation, and preterm delivery. Acta Obstet Gynecol Scand 1997; 76: 38–44.

    CrossRef  CAS  Google Scholar 

  54. Olsen SF, Hansen HS, Secher NJ, Jensen B, Sandstrom B. Gestation length and birth weight in relation to intake of marine n-3 fatty acids. Br J Nutrit 1995; 73: 397–404.

    CrossRef  CAS  Google Scholar 

  55. Caulfield LE, Zavaleta N, Figueroa A, Leon Z. Maternal zinc supplementation does not affect size at birth or pregnancy duration in Peru. J Nutr 1999; 129: 1563–1568.

    CAS  Google Scholar 

  56. Fawzi WW, Msamanga GI, Spiegelman D, Urassa EJ, McGrath N, Mwakagile D, et al. Randomized trial of effects of vitamin supplements on pregnancy outcomes and T cell counts in HIV-infected women in Tanzania. Lancet 1998; 351: 1477–1482.

    CrossRef  CAS  Google Scholar 

  57. Carmichael SL, Abrams B. A critical review of the relationship between gestational weight gain and pre-term delivery. Obstet Gynecol 1997; 89: 865–873.

    CrossRef  CAS  Google Scholar 

  58. Naeye RL. Maternal body weight and pregnancy outcome. Am J Clin Nutr 1990; 52: 273–279.

    CAS  Google Scholar 

  59. Little RE, Weinberg CR. Risk factors for antepartum and intrapartum stillbirth. Am J Epidemiol 1993; 137: 1177–1189.

    CAS  Google Scholar 

  60. Lucas A, Morley R, Cole TJ, et al. Maternal fatness and viability of preterm infants. BMJ 1988; 296: 1495–1497.

    CrossRef  CAS  Google Scholar 

  61. Cnattingius, S, Bergstrom R, Lipworth L, Kramer MS. Prepregnancy weight and the risk of adverse pregnancy outcomes. N Engl J Med 1998; 338: 147–152.

    CrossRef  CAS  Google Scholar 

  62. Barros FC, Victora CG, Vaughan JP, Estanislasu HJ. Perinatal mortality in southern Brazil: a population-based study of 7,392 births. Bull WHO 1987; 65: 95–104.

    CAS  Google Scholar 

  63. Barros FC, Vaughan JP, Victora CG, Huttly SRA. An epidemic of caesarean sections in Brazil? The influence of tubal ligations and socioeconomic status. Lancet 1991; 338: 167–169.

    CrossRef  CAS  Google Scholar 

  64. WHO. Obesity: Preventing and Managing the Global Epidemic. Geneva: WHO, 1998.

    Google Scholar 

  65. Udall, JN, Harrison GG, Vaucher Y, Walson PD, Morrow GIII. Interaction of maternal and neonatal obesity. Pediatrics 1978; 62: 17–21.

    CAS  Google Scholar 

  66. Ounsted M, Scott A. Associations between maternal weight, height, weight-for-height, weight-gain and birth weight. In: Maternal Nutrition in Pregnancy Eating for Two? Dobbing J, ed. Academic, London, 1981 pp. 113–129.

    Google Scholar 

  67. Wolfe HM, Zador IE, Gross TL, Martier SS, Sokol RJ. The clinical utility of maternal body mass index in pregnancy. Am J Obstet Gynecol 1991; 164: 1306–1310.

    CrossRef  CAS  Google Scholar 

  68. Kramer MS, Olivier M, McLean FH, Willis DM, Usher RH. The impact of intrauterine growth retardation and body proportionality on fetal and neonatal outcome. Pediatrics 1990; 85: 707–713.

    Google Scholar 

  69. Bang AT, Bang RA, Baitule SB, Reddy MH, Deshmukh MD. Effect of home-based neonatal care and management of sepsis on neonatal mortality: field trial in rural India. Lancet 1999; 354: 1955–1961.

    CrossRef  CAS  Google Scholar 

  70. MRC Vitamin Study Research Group Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991; 338:131–137.

    Google Scholar 

  71. Berry RJ, Li Z, Erickson JD, Li S, Moore CA, Wang H, et al. Prevention of neural-tube defects with folic acid in China. N Engl J Med 1999; 341: 1485–1490.

    CrossRef  CAS  Google Scholar 

  72. Kramer MS, Haas J, Kelly A. Maternal anthropometry-based screening and pregnancy outcome: a decision analysis. Trop Med Intl Health 1998; 3: 447–453.

    CrossRef  CAS  Google Scholar 

  73. Kramer MS. The effects of energy and protein intake on pregnancy outcome: an overview of the research evidence from controlled clinical trials. Am J Clin Nutr 1993; 58: 627–635.

    CAS  Google Scholar 

  74. Rose G. Strategy of prevention: lessons from cardiovascular disease. BMJ 1981; 282: 1847–1851.

    CrossRef  CAS  Google Scholar 

  75. Rose G. Sick individuals and sick populations. Intl J Epidemiol 1985; 14: 32–38.

    CrossRef  CAS  Google Scholar 

  76. Haas JD, Murdoch S, Rivera J, Martorell R. Early nutrition and later physical work capacity. Nutr Rev 1996; 54 (2 Pt 2): S41–S48.

    CAS  Google Scholar 

  77. Martorell R, Ramakrishnan U, Schroeder DG, Ruel M. Reproductive performance and nutrition during childhood. Nutr Rev 1996; 54 (4 Pt 2): S15–S21.

    CAS  Google Scholar 

  78. Subcommittee on Nutritional Status and Weight Gain During Pregnancy, Food and Nutrition Board, U.S. Institute of Medicine/National Academy of Sciences. Nutrition During Pregnancy. Washington, DC: National Academy Press, 1990.

    Google Scholar 

  79. Galuska DA, Serdula M, Pamuk E, Siegel PZ, Byers T. Trends in overweight among US adults from 1987 to 1993. Am J Public Health 1996; 86: 1729–1735.

    Google Scholar 

  80. Kuczmarski RJ, Flegal KM, Campbell SM, Johnson CL. Increasing prevalence of overweight among US adults. JAMA 1994; 272: 205–211.

    CrossRef  CAS  Google Scholar 

  81. Kuskowska-Wolk A, Bergstrom R. Trends in body mass index and prevalence of obesity in Swedish women 1980–89. J Epidemiol Comm Health 1993; 47: 195–199.

    CrossRef  CAS  Google Scholar 

  82. Skodova Z, Pisa Z, Emrova R, et al. Cardiovascular risk factors in the Czech population. Cor Vasa 1991; 33: 114–122.

    CAS  Google Scholar 

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Kramer, M.S., Victora, C.G. (2001). Low Birth Weight and Perinatal Mortality. In: Semba, R.D., Bloem, M.W. (eds) Nutrition and Health in Developing Countries. Nutrition ◊ and ◊ Health. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-225-8_3

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  • DOI: https://doi.org/10.1007/978-1-59259-225-8_3

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