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Signaling Networks and Cell Cycle Control pp 231–245Cite as

Signaling Pathways Controlled by Rho Family GTP-Binding Proteins

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Part of the book series: Cancer Drug Discovery and Development ((CDD&D))

Abstract

The current Rho family picture contains 11 mammalian members, which can be subdivided into five groups on the basis of sequence and functional differences: (1) RhoA, RhoB, and RhoC; (2) Rac1, Rac2, and RhoG; (3) Cdc42 and TC10; (4) RhoD; and (5) RhoE and TTF (1,2). In addition, homologs of several of these GTPases have been identified and functionally characterized in lower organisms ranging from yeast to the fruit fly (1).

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  1. Marc Symons PhD
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Editors and Affiliations

  1. Oral and Pharyngeal Cancer Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA

    J. Silvio Gutkind PhD

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© 2000 Humana Press Inc., Totowa, NJ

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Symons, M. (2000). Signaling Pathways Controlled by Rho Family GTP-Binding Proteins. In: Gutkind, J.S. (eds) Signaling Networks and Cell Cycle Control. Cancer Drug Discovery and Development. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-218-0_13

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  • DOI: https://doi.org/10.1007/978-1-59259-218-0_13

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-4684-9695-6

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