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Role of Growth Factors in the Treatment of Diabetic Foot Ulceration

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The Diabetic Foot
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Abstract

Wound healing is the process of tissue repair and the tissue response to injury. It is a complex biologic process involving chemotaxis, cellular reproduction, matrix protein, neovascularization, and scar remodeling (1). Much progress has been made in our understanding of the cellular and molecular biology of wound repair and remodeling in recent years, yet many aspects about wound healing remain unclear. Growth factors are polypeptides that control the growth, differentiation, and metabolism of cells and regulate the process of tissue repair (2,3). The role of growth factors in wound healing and specifically in diabetic ulcer healing is the subject of this chapter.

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© 2002 Springer Science+Business Media New York

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Steed, D.L. (2002). Role of Growth Factors in the Treatment of Diabetic Foot Ulceration. In: Veves, A., Giurini, J.M., LoGerfo, F.W. (eds) The Diabetic Foot. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-168-8_18

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  • DOI: https://doi.org/10.1007/978-1-59259-168-8_18

  • Publisher Name: Humana Press, Totowa, NJ

  • Print ISBN: 978-1-61737-253-7

  • Online ISBN: 978-1-59259-168-8

  • eBook Packages: Springer Book Archive

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