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Vesicular Neurotransmitter Transporters

Pharmacology, Biochemistry, and Molecular Analysis

  • Chapter
Neurotransmitter Transporters

Part of the book series: Contemporary Neuroscience ((CNEURO))

Abstract

Synaptic transmission involves the regulated release of transmitter molecules to the synaptic cleft, where they interact with postsynaptic receptors which subsequently transduce the information. Removal of the transmitter from the cleft enables termination of the signal, which usually occurs through reuptake back to the presynaptic terminal or into glial elements in a sodium-dependent process. This process assures constant and high levels of neurotransmitters in the neuron and low concentrations in the cleft.

Chapter authored in August 2000.

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Authors
  1. Rodrigo Yelin
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  2. Shimon Schuldiner
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  1. Department of Biomedical and Therapeutic Sciences, University of Illinois College of Medicine, Peoria, IL, USA

    Maarten E. A. Reith

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Yelin, R., Schuldiner, S. (2002). Vesicular Neurotransmitter Transporters. In: Reith, M.E.A. (eds) Neurotransmitter Transporters. Contemporary Neuroscience. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-158-9_9

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