Peptide Sequence Analysis by Tandem Mass Spectrometry
In the last chapter, we considered protein identification with an m/z measurement of the tryptic peptide VGAHAGEYGAEALER from human hemoglobin alpha. When we searched a human/mouse protein sequence database, we found two “perfect” hits for this peptide, both of which had m/z 1529.7384 for the [M+H]+ ion. Both corresponded to hemoglobin alpha peptides that are highly conserved between mice and men:
The human: VGAHAGEYGAEALER
The mouse: IGGHGAEYGAEALER
KeywordsPeptide Amide Alpha Carbon Hemoglobin Alpha Proline Peptide Bond Amino Acid Residue Masse
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© Springer Science+Business Media New York 2002