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Serum and Urine Paraprotein Capillary Electrophoresis

  • Carl R. Jolliff
Part of the Pathology and Laboratory Medicine book series (PLM)

Abstract

Most requests for serum and urine electrophoresis occur because of the reversal of albumin/globulin ratios in the general chemistry profile or the presence of protein in the urine. The suspicion of possible myelomatosis by the physician also alerts him/her to rule out the presence of a monoclonal gammopathy in the serum or light chain in the urine. Because of the increased sensitivity afforded by the newer electrophoresis systems, paraproteins are found more often. Their appearance in a number of conditions exhibiting a B-cell lymphoproliferative response has renewed the interest of oncologists, hematologists, nephrologists, rheumatologists, internists, and neurologists.

Keywords

Capillary Electrophoresis Capillary Zone Electrophoresis Monoclonal Gammopathy Free Light Chain Sepharose Bead 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 2001

Authors and Affiliations

  • Carl R. Jolliff

There are no affiliations available

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