Gastroesophageal Reflux Disease

Epidemiology and Pathophysiology
  • Philip O. Katz
  • Amine Hila
Part of the Clinical Gastroenterology book series (CG)


Gastroesophageal reflux disease (GERD) encompasses a spectrum of disorders in which gastric reflux leads to symptoms and/or damage to the esophageal mucosa. For the most part, it is a clinical diagnosis that may be objectively confirmed by a number of diagnostic tests. Presentations of GERD may vary widely, but can be divided into three categories: typical symptoms (heartburn and regurgitation), atypical symptoms (angina-like chest pain, asthma, cough, and laryngitis) and complications (ulcerations, strictures, and metaplastic changes or Barrett’s esophagus).


Hiatal Hernia Lower Esophageal Sphincter Gastroesophageal Reflux Disease Reflux Esophagitis Reflux Symptom 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Humana Press Inc., Totowa, NJ 2001

Authors and Affiliations

  • Philip O. Katz
  • Amine Hila

There are no affiliations available

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