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Drug Interactions in Infectious Diseases pp 13–38Cite as

Mechanisms of Drug Interactions

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Part of the book series: Infectious Disease ((ID))

Abstract

One hundred and fifty million outpatient prescriptions for antibiotics are dispensed each year in the United States (1). In institutional settings, 25–35% of hospitalized patients receive antibiotic treatment for active infections or to prevent infections (2). Given that antibiotics represent global sales of approximately $20 billion of a $370 billion pharmaceutical market, one can assume that many patients who are prescribed antibiotics are also receiving other agents (3). Therefore, the potential for drug interactions is significant.

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Authors
  1. Angela D. M. Kashuba
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  2. Joseph S. Bertino Jr.
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Editors and Affiliations

  1. Clinical Pharmacokinetics Research Laboratory, Clinical Center Pharmacy Department, National Institutes of Health, Bethesda, MD, USA

    Stephen C. Piscitelli Pharm.D. (Coordinator) (Coordinator)

  2. Pharmacy College of Pharmacy and Medicine, University of Illinois at Chicago, Chicago, IL, USA

    Keith A. Rodvold Pharm.D. (Professor of Pharmacy Practice and Associate Professor of Medicine) (Professor of Pharmacy Practice and Associate Professor of Medicine)

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Kashuba, A.D.M., Bertino, J.S. (2001). Mechanisms of Drug Interactions. In: Piscitelli, S.C., Rodvold, K.A. (eds) Drug Interactions in Infectious Diseases. Infectious Disease. Humana Press, Totowa, NJ. https://doi.org/10.1007/978-1-59259-025-4_2

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  • DOI: https://doi.org/10.1007/978-1-59259-025-4_2

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