Refractory Hypertension

  • C. Venkata S. Ram
Part of the Current Clinical Practice book series (CCP)


Because of widespread treatment of systemic hypertension, true refractory hypertension is somewhat unusual in the current management of hypertensive disorders. A majority of patients with uncomplicated primary hypertension respond to one or two drugs. Hypertension is considered refractory if the blood pressure (BP) cannot be reduced below 140/90 mmHg in patients who are compliant with an appropriate triple-drug regimen that includes a diuretic, with all the components prescribed in near maximal or tolerated doses. For patients with isolated systolic hypertension, refractoriness is defined as a failure of an adequate triple-drug regimen to reduce systolic blood pressure below 160 mmHg.


Obstructive Sleep Apnea Resistant Hypertension Renovascular Hypertension Target Organ Damage White Coat Hypertension 
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© Springer Science+Business Media New York 2001

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  • C. Venkata S. Ram

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