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Hepatitis A, B, and C

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Principles and Practice of Transplant Infectious Diseases

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Abstract

Viral hepatitis remains the leading cause of liver failure and is the primary indication for liver transplantation worldwide. Hepatitis viruses are categorized into five distinct subtypes that collectively render significant morbidity and mortality in transplanted patients. Each subtype has a distinct replication pattern, pathology, and treatment. While the primary pathology mediated by these viruses occurs within the liver, significant extrahepatic disease may be observed with particular subtypes of hepatitis and warrant special treatment modalities prior to and following transplantation. Advances in the management of hepatitis B and C have recently revolutionized the treatment paradigm from supportive care to cure. In this section, each hepatitis subtype is described separately and accompanied by diagnostic and treatment strategies with emphasis on care for the transplanted patient.

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Authors and Affiliations

  1. Department of Surgery, Yale School of Medicine, Yale-New Haven Hospital, New Haven, CT, USA

    Jonathan Merola

  2. Division of Gastroenterology, Mid-Atlantic Kaiser Permanente Medical Group, Springfield, VA, USA

    Alexander Z. Jow

  3. Division of Gastroenterology and Hepatology, Department of Medicine, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA

    Samuel H. Sigal

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  1. Clinical Associate Professor of Medicine, Texas Tech University Health Sciences Center El Paso, Paul L. Foster School of Medicine, El Paso, TX, USA

    Amar Safdar

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Merola, J., Jow, A.Z., Sigal, S.H. (2019). Hepatitis A, B, and C. In: Safdar, A. (eds) Principles and Practice of Transplant Infectious Diseases. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-9034-4_41

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