Nerve Sheath and Related Tumors



This chapter reviews the wide spectrum of cutaneous nerve sheath tumors. The vast majority are benign tumors, including neurofibromas, schwannomas, perineuriomas, granular cell tumors, and various neuroma subtypes. Malignant granular cell tumor, malignant peripheral nerve sheath tumor, and Ewing sarcoma, a malignant neuroectodermal tumor, are also rarely encountered in the skin. Diagnostic criteria and practical considerations are emphasized.


Neurofibroma Schwannoma Perineurioma Granular cell tumor Solitary circumscribed neuroma Meningioma Malignant peripheral nerve sheath tumor Ewing sarcoma 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of PathologyCleveland ClinicClevelandUSA

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