Abstract
There is considerable information available about biomarkers of metabolic disorders. The use of some of these biomarkers is well established. Coverage of all metabolic disorders is beyond the scope of this report. Example of acute intermittent porphyria, liver X receptors, diabetes and the metabolic syndrome will be discussed in this section.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Chen HB, Jia WP. Biomarkers for diabetes prediction, diagnosis and personalized therapy. Chin Med J. 2012;125:4163–6.
Delaby C, To-Figueras J, Deybach JC, et al. Role of two nutritional hepatic markers (insulin-like growth factor 1 and transthyretin) in the clinical assessment and follow-up of acute intermittent porphyria patients. J Intern Med. 2009;266:277–85.
Domingueti CP, Dusse LM, Carvalho MD, et al. Diabetes mellitus: the linkage between oxidative stress, inflammation, hypercoagulability and vascular complications. J Diabetes Complicat. 2016;30:738–45.
Kuhtreiber WM, Washer SL, Hsu E, et al. Low levels of C-peptide have clinical significance for established type 1 diabetes. Diabet Med. 2015;32:1346–53.
Li J, Song J, Zaytseva YY, et al. An obligatory role for neurotensin in high-fat-diet-induced obesity. Nature. 2016;533:411–5.
Magnusson M, Hedblad B, Engström G, et al. High levels of cystatin C predict the metabolic syndrome: the prospective Malmö diet and cancer study. J Intern Med. 2013;274:192–9.
Neutzsky-Wulff AV, Andreassen KV, Hjuler ST, et al. Future detection and monitoring of diabetes may entail analysis of both β-cell function and volume: how markers of β-cell loss may assist. J Transl Med. 2012;10:214.
Nowak C, Sundström J, Gustafsson S, et al. Protein biomarkers for insulin resistance and type 2 diabetes risk in two large community cohorts. Diabetes. 2016;65:276–84.
Quehenberger O, Dennis EA. The human plasma lipidome. N Engl J Med. 2011;365:1812–23.
Sardh E, Harper P, Andersson DE, Floderus Y. Plasma porphobilinogen as a sensitive biomarker to monitor the clinical and therapeutic course of acute intermittent porphyria attacks. Eur J Intern Med. 2009;20:201–7.
Vacca M, D'Amore S, Graziano G, et al. Clustering nuclear receptors in liver regeneration identifies candidate modulators of hepatocyte proliferation and hepatocarcinoma. PLoS One. 2014;9(8):e104449.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 2017 Springer Science+Business Media LLC
About this chapter
Cite this chapter
Jain, K.K. (2017). Biomarkers in Metabolic Disorders. In: The Handbook of Biomarkers. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-7431-3_6
Download citation
DOI: https://doi.org/10.1007/978-1-4939-7431-3_6
Published:
Publisher Name: Humana Press, New York, NY
Print ISBN: 978-1-4939-7430-6
Online ISBN: 978-1-4939-7431-3
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)