Computer Simulations and Nonlinear Dynamics of Cardiac Action Potentials

  • Daisuke SatoEmail author
Part of the Handbook of Modern Biophysics book series (HBBT, volume 5)


Sudden cardiac death accounts for >300,000 deaths per year in the United States alone. However, several clinical trials failed and tested drugs increased molarity. Therefore, deeper understanding of the mechanisms of arrhythmias is required. The goals of this chapter are (1) to learn how to make a mathematical model of the cardiac action potential, (2) to learn how to simulate the model and analyze the dynamics, (3) to learn how to parallelize the code to simulate computationally intensive models.


Graphic Processing Unit Action Potential Duration Spiral Wave Cardiac Action Potential Inactivation Gate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



I would like to acknowledge funding support from National Institutes of Health grant R00-HL111334, American Heart Association Grant-in-Aid 16GRNT31300018, and Amazon AWS Cloud Credits for Research.


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© Springer Science+Business Media LLC 2017

Authors and Affiliations

  1. 1.Department of PharmacologyUniversity of California, DavisDavisUSA

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